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Why 6-Iodouridine Cannot Be Used as a Radiosensitizer of DNA Damage? Computational and Experimental Studies
[Image: see text] Previous density functional theory (DFT) studies on 6-brominated pyrimidine nucleosides suggest that 6-iodo-2′-deoxyuridine (6IdU) should act as a better radiosensitizer than its 5-iodosubstituted 2′-deoxyuridine analogue. In this work, we show that 6IdU is unstable in an aqueous s...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041638/ https://www.ncbi.nlm.nih.gov/pubmed/36893332 http://dx.doi.org/10.1021/acs.jpcb.3c00548 |