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Prospective, longitudinal analysis of the gut microbiome in patients with locally advanced rectal cancer predicts response to neoadjuvant concurrent chemoradiotherapy

BACKGROUND: Neoadjuvant concurrent chemoradiotherapy (nCCRT) is a standard treatment for locally advanced rectal cancer (LARC). The gut microbiome may be reshaped by radiotherapy through its effects on microbial composition, mucosal immunity, and the systemic immune system. We sought to clarify dyna...

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Detalles Bibliográficos
Autores principales: Sun, Yi, Zhang, Xiang, Jin, Chuandi, Yue, Kaile, Sheng, Dashuang, Zhang, Tao, Dou, Xue, Liu, Jing, Jing, Hongbiao, Zhang, Lei, Yue, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041716/
https://www.ncbi.nlm.nih.gov/pubmed/36967379
http://dx.doi.org/10.1186/s12967-023-04054-1