TERRA G-quadruplex stabilization as a new therapeutic strategy for multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a hematologic malignancy characterized by high genomic instability, and telomere dysfunction is an important cause of acquired genomic alterations. Telomeric repeat-containing RNA (TERRA) transcripts are long non-coding RNAs involved in telomere stability through...

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Detalles Bibliográficos
Autores principales: Scionti, Francesca, Juli, Giada, Rocca, Roberta, Polerà, Nicoletta, Nadai, Matteo, Grillone, Katia, Caracciolo, Daniele, Riillo, Caterina, Altomare, Emanuela, Ascrizzi, Serena, Caparello, Basilio, Cerra, Maria, Arbitrio, Mariamena, Richter, Sara N., Artese, Anna, Alcaro, Stefano, Tagliaferri, Pierosandro, Tassone, Pierfrancesco, Di Martino, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041726/
https://www.ncbi.nlm.nih.gov/pubmed/36967378
http://dx.doi.org/10.1186/s13046-023-02633-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041726/
https://www.ncbi.nlm.nih.gov/pubmed/36967378
http://dx.doi.org/10.1186/s13046-023-02633-0

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