Complement C3 mediates podocyte injury through TLR4/NFΚB-P65 signaling during ischemia–reperfusion acute kidney injury and post-injury fibrosis

BACKGROUND: The aim of this study was to explore the mechanism of complement C3a mediating podocyte injury during ischemia–reperfusion acute kidney injury (IR-AKI) and post-injury fibrosis. METHODS: Renal artery clamping was used to establish IR-AKI and post-injury fibrosis model. HE and Masson stai...

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Detalles Bibliográficos
Autores principales: Chen, Yi, Lin, Liyu, Rao, Siyi, Tao, Xuan, Cui, Jiong, Wan, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041728/
https://www.ncbi.nlm.nih.gov/pubmed/36973754
http://dx.doi.org/10.1186/s40001-023-01054-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041728/
https://www.ncbi.nlm.nih.gov/pubmed/36973754
http://dx.doi.org/10.1186/s40001-023-01054-1

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