Daurisoline attenuates H(2)O(2)-induced chondrocyte autophagy by activating the PI3K/Akt/mTOR signaling pathway

BACKGROUND: Osteoarthritis (OA) is a chronic degenerative joint disease characterized by cartilage degeneration and intra-articular inflammation. Daurisoline (DAS) is an isoquinoline alkaloid isolated from Rhizoma Menispermi, whose antitumor and anti-inflammatory pharmacological effects have been de...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Liu, Wenguang, Liu, Zhonghao, Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041752/
https://www.ncbi.nlm.nih.gov/pubmed/36973772
http://dx.doi.org/10.1186/s13018-023-03717-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041752/
https://www.ncbi.nlm.nih.gov/pubmed/36973772
http://dx.doi.org/10.1186/s13018-023-03717-5

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