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Daurisoline attenuates H(2)O(2)-induced chondrocyte autophagy by activating the PI3K/Akt/mTOR signaling pathway

BACKGROUND: Osteoarthritis (OA) is a chronic degenerative joint disease characterized by cartilage degeneration and intra-articular inflammation. Daurisoline (DAS) is an isoquinoline alkaloid isolated from Rhizoma Menispermi, whose antitumor and anti-inflammatory pharmacological effects have been de...

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Detalles Bibliográficos
Autores principales:	Zhang, Yang, Liu, Wenguang, Liu, Zhonghao, Liu, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041752/ https://www.ncbi.nlm.nih.gov/pubmed/36973772 http://dx.doi.org/10.1186/s13018-023-03717-5

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