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Statistical methods for exploring spontaneous adverse event reporting databases for drug-host factor interactions
BACKGROUND: Drug toxicity does not affect patients equally; the toxicity may only exert in patients who possess certain attributes of susceptibility to specific drug properties (i.e., drug-host interaction). This concept is crucial for personalized drug safety but remains under-studied, primarily du...
Autores principales: | Lu, Zhiyuan, Suzuki, Ayako, Wang, Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041785/ https://www.ncbi.nlm.nih.gov/pubmed/36973693 http://dx.doi.org/10.1186/s12874-023-01885-w |
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