PINK1/Parkin-Mediated Mitochondrial Autophagy Participates in H(2)O(2)-Induced Abnormal Proliferation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis

INTRODUCTION: To explore the role of PINK1/Parkin-mediated mitochondrial autophagy in H(2)O(2)-induced abnormal proliferation of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS). METHODS: Firstly, we isolated fibroblast like synoviocytes (RA-FLS) from RA patients. H(2)O(2)-induced oxidativ...

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Detalles Bibliográficos
Autores principales: Wang, Gaoyuan, Chen, Xiaoyu, Shao, Yubao, Xu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042253/
https://www.ncbi.nlm.nih.gov/pubmed/36993991
http://dx.doi.org/10.2147/JIR.S398690

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