Cargando…
Docking cholesterol to integral membrane proteins with Rosetta
Lipid molecules such as cholesterol interact with the surface of integral membrane proteins (IMP) in a mode different from drug-like molecules in a protein binding pocket. These differences are due to the lipid molecule’s shape, the membrane’s hydrophobic environment, and the lipid’s orientation in...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042369/ https://www.ncbi.nlm.nih.gov/pubmed/36972273 http://dx.doi.org/10.1371/journal.pcbi.1010947 |