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Can autofluorescence and fluorescence imaging be useful in fight with COVID-19 pandemia?

The entire medical world gathers information related to the COVID-19 pandemic, including its spread analysis, disease characteristics, morbidity and mortality statistics, as well as factors limiting and promoting infection and severe course, and above all potential treatment options. Scientific rese...

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Autores principales: KWIATEK, Sebastian, DUBIK, Paweł, CESARZ, Karolina, ZIĘTEK, Piotr, SIEROŃ, Aleksander, SIEROŃ, Karolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042534/
http://dx.doi.org/10.1016/j.pdpdt.2023.103452
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author KWIATEK, Sebastian
DUBIK, Paweł
CESARZ, Karolina
ZIĘTEK, Piotr
SIEROŃ, Aleksander
SIEROŃ, Karolina
author_facet KWIATEK, Sebastian
DUBIK, Paweł
CESARZ, Karolina
ZIĘTEK, Piotr
SIEROŃ, Aleksander
SIEROŃ, Karolina
author_sort KWIATEK, Sebastian
collection PubMed
description The entire medical world gathers information related to the COVID-19 pandemic, including its spread analysis, disease characteristics, morbidity and mortality statistics, as well as factors limiting and promoting infection and severe course, and above all potential treatment options. Scientific research is being carried out on a large scale on methods of early detection of COVID-19 infection, including imaging methods such as computed tomography or ultrasound imaging. The importance of imaging methods is increasingly emphasized in the literature as sensitive and specific, often with greater clinical utility than mass-applied serological tests. Especially in large urban agglomerations such as Silesia, the wide availability of these imaging methods as screening methods in the clinical assessment of potentially infectious patients seems to be important. The literature on the COVID-19 epidemic emphasizes the significant role of integrated diagnostic methods including basic science as well as radiological and endoscopic imaging methods in the diagnosis of COVID-19 infection and its possible complications. The study presents potential possibilities of using the phenomena of autofuorescence and fluorescence in supporting the diagnosis of patients with suspected COVID-19 infection. The study presents preliminary results of case studies of patients suspected of being infected with COVID-19, and shows the multidimensional application of fluorescent phenomena in supporting diagnostics. One of the main tools used in the study is autofluorescent bronchoscopy as a method that, in synchronization with high resolution tomography analysis, significantly facilitates obtaining representative material for RT-PCR. The study also showed the potential for assessing fluorescent material under fluorescence microscopy, which can significantly facilitate diagnostics in the future and speed up existing screening tests to complement genetic diagnostics.
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spelling pubmed-100425342023-03-28 Can autofluorescence and fluorescence imaging be useful in fight with COVID-19 pandemia? KWIATEK, Sebastian DUBIK, Paweł CESARZ, Karolina ZIĘTEK, Piotr SIEROŃ, Aleksander SIEROŃ, Karolina Photodiagnosis Photodyn Ther Article The entire medical world gathers information related to the COVID-19 pandemic, including its spread analysis, disease characteristics, morbidity and mortality statistics, as well as factors limiting and promoting infection and severe course, and above all potential treatment options. Scientific research is being carried out on a large scale on methods of early detection of COVID-19 infection, including imaging methods such as computed tomography or ultrasound imaging. The importance of imaging methods is increasingly emphasized in the literature as sensitive and specific, often with greater clinical utility than mass-applied serological tests. Especially in large urban agglomerations such as Silesia, the wide availability of these imaging methods as screening methods in the clinical assessment of potentially infectious patients seems to be important. The literature on the COVID-19 epidemic emphasizes the significant role of integrated diagnostic methods including basic science as well as radiological and endoscopic imaging methods in the diagnosis of COVID-19 infection and its possible complications. The study presents potential possibilities of using the phenomena of autofuorescence and fluorescence in supporting the diagnosis of patients with suspected COVID-19 infection. The study presents preliminary results of case studies of patients suspected of being infected with COVID-19, and shows the multidimensional application of fluorescent phenomena in supporting diagnostics. One of the main tools used in the study is autofluorescent bronchoscopy as a method that, in synchronization with high resolution tomography analysis, significantly facilitates obtaining representative material for RT-PCR. The study also showed the potential for assessing fluorescent material under fluorescence microscopy, which can significantly facilitate diagnostics in the future and speed up existing screening tests to complement genetic diagnostics. Published by Elsevier B.V. 2023-03 2023-03-27 /pmc/articles/PMC10042534/ http://dx.doi.org/10.1016/j.pdpdt.2023.103452 Text en Copyright © 2023 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
KWIATEK, Sebastian
DUBIK, Paweł
CESARZ, Karolina
ZIĘTEK, Piotr
SIEROŃ, Aleksander
SIEROŃ, Karolina
Can autofluorescence and fluorescence imaging be useful in fight with COVID-19 pandemia?
title Can autofluorescence and fluorescence imaging be useful in fight with COVID-19 pandemia?
title_full Can autofluorescence and fluorescence imaging be useful in fight with COVID-19 pandemia?
title_fullStr Can autofluorescence and fluorescence imaging be useful in fight with COVID-19 pandemia?
title_full_unstemmed Can autofluorescence and fluorescence imaging be useful in fight with COVID-19 pandemia?
title_short Can autofluorescence and fluorescence imaging be useful in fight with COVID-19 pandemia?
title_sort can autofluorescence and fluorescence imaging be useful in fight with covid-19 pandemia?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042534/
http://dx.doi.org/10.1016/j.pdpdt.2023.103452
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