Cargando…

AAV1.NT-3 gene therapy prevents age-related sarcopenia

Sarcopenia is progressive loss of muscle mass and strength, occurring during normal aging with significant consequences on the quality of life for elderly. Neurotrophin 3 (NT-3) is an important autocrine factor supporting Schwann cell survival and differentiation and stimulating axon regeneration an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ozes, Burcak, Tong, Lingying, Myers, Morgan, Moss, Kyle, Ridgley, Alicia, Sahenk, Zarife
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042697/ https://www.ncbi.nlm.nih.gov/pubmed/36897179 http://dx.doi.org/10.18632/aging.204577

Ejemplares similares

AAV1.NT‐3 gene therapy in the SOD1KO mouse model of accelerated sarcopenia
por: Tong, Lingying, et al.
Publicado: (2023)

AAV1.NT-3 gene therapy in a CMT2D model: phenotypic improvements in Gars(P278KY/+) mice
por: Ozes, Burcak, et al.
Publicado: (2021)

AAV1.NT-3 gene therapy for X-linked Charcot–Marie–Tooth neuropathy type 1
por: Ozes, Burcak, et al.
Publicado: (2021)

Systemic delivery of AAVrh74.tMCK.hCAPN3 rescues the phenotype in a mouse model for LGMD2A/R1
por: Sahenk, Zarife, et al.
Publicado: (2021)

AAV1.NT-3 Gene Therapy for Charcot–Marie–Tooth Neuropathy
por: Sahenk, Zarife, et al.
Publicado: (2014)

AAV1.NT-3 gene therapy attenuates spontaneous autoimmune peripheral polyneuropathy
por: Yalvac, M E, et al.
Publicado: (2016)

Pre-clinical Safety and Off-Target Studies to Support Translation of AAV-Mediated RNAi Therapy for FSHD
por: Wallace, Lindsay M., et al.
Publicado: (2017)

AAV.Dysferlin Overlap Vectors Restore Function in Dysferlinopathy Animal Models
por: Sondergaard, Patricia C, et al.
Publicado: (2015)

Vasculitic neuropathy associated with IgG4-related kidney disease: A case report and literature review
por: Jiang, Benjamin, et al.
Publicado: (2021)

A novel p.T139M mutation in HSPB1 highlighting the phenotypic spectrum in a family
por: Amornvit, Jakkrit, et al.
Publicado: (2017)

AAV-mediated NT-3 overexpression protects cochleae against noise-induced synaptopathy
por: Chen, Hengchao, et al.
Publicado: (2018)

Follistatin Gene Therapy Improves Ambulation in Becker Muscular Dystrophy
por: Al-Zaidy, Samiah A., et al.
Publicado: (2015)

Antidepressant effect of recombinant NT4-NAP/AAV on social isolated mice through intranasal route
por: Liu, Fei, et al.
Publicado: (2016)

Positive regulation of TNFR1 signaling via SH3 recognition motif
por: ÇOPUROĞLU, Fatma Ece, et al.
Publicado: (2021)

AAV‐Mediated nuclear localized PGC1α4 delivery in muscle ameliorates sarcopenia and aging‐associated metabolic dysfunctions
por: Guo, Mingwei, et al.
Publicado: (2023)

Age‐related alterations in muscle architecture are a signature of sarcopenia: the ultrasound sarcopenia index
por: Narici, Marco, et al.
Publicado: (2021)

Hospital‐associated sarcopenia, acute sarcopenia, and iatrogenic sarcopenia: Prevention of sarcopenia during hospitalization
por: Wakabayashi, Hidetaka
Publicado: (2023)

Sarcopenia and Endocrine Ageing: Are They Related?
por: Gupta, Prishita, et al.
Publicado: (2022)

Clostridium novyi-NT in cancer therapy
por: Staedtke, Verena, et al.
Publicado: (2016)

The role of obesity in sarcopenia and the optimal body composition to prevent against sarcopenia and obesity
por: Liu, Chaoran, et al.
Publicado: (2023)

Efficacy of exogenous pyruvate in Trembler(J) mouse model of Charcot‐Marie‐Tooth neuropathy
por: Sahenk, Zarife, et al.
Publicado: (2018)

SIK2 attenuates proliferation and survival of breast cancer cells with simultaneous perturbation of MAPK and PI3K/Akt pathways
por: Zohrap, Neslihan, et al.
Publicado: (2018)

Anti-AAV Antibodies in AAV Gene Therapy: Current Challenges and Possible Solutions
por: Weber, Thomas
Publicado: (2021)

Optimizing intrinsic capacity to prevent frailty and sarcopenia in old age
por: Chhetri, Jagadish K., et al.
Publicado: (2023)

PUMILIO hyperactivity drives premature aging of Norad-deficient mice
por: Kopp, Florian, et al.
Publicado: (2019)

Sarcopenia and Age-Related Endocrine Function
por: Sakuma, Kunihiro, et al.
Publicado: (2012)

The Role of Inflammation in Age-Related Sarcopenia
por: Dalle, Sebastiaan, et al.
Publicado: (2017)

Role of exercise in age-related sarcopenia
por: Yoo, Su-Zi, et al.
Publicado: (2018)

Orthostatic hypotension and age-related sarcopenia
por: Keskin, Kudret, et al.
Publicado: (2021)

Building intranets on NT, NetWare and Solaris : an administrator's guide
por: Stern, Morgan
Publicado: (1997)

Immunogenicity and toxicity of AAV gene therapy
por: Ertl, Hildegund C. J.
Publicado: (2022)

AAV gene therapy vectors in the TMJ
por: Brouxhon, Sabine M., et al.
Publicado: (2022)

Effects of Nt-truncation and coexpression of isolated Nt domains on the membrane trafficking of electroneutral Na(+)/HCO(3)(–) cotransporters
por: Wang, Deng-Ke, et al.
Publicado: (2015)

AAV-8 and AAV-9 Vectors Cooperate with Serum Proteins Differently Than AAV-1 and AAV-6
por: Denard, Jérôme, et al.
Publicado: (2018)

Strategies to Prevent Sarcopenia in the Aging Process: Role of Protein Intake and Exercise
por: Rogeri, Patricia S., et al.
Publicado: (2021)

3D culture adds an extra dimension to targeted epigenetic therapies
por: Ozes, Ali R, et al.
Publicado: (2013)

CDEV-NT: Porting the Control Device Interface to Windows NT
por: Akers, W, et al.
Publicado: (1999)

The Baikal neutrino experiment: from NT200 to NT200+
por: Aynutdinov, V
Publicado: (2005)

The role of nutrition in the prevention of sarcopenia
por: Robinson, Sian, et al.
Publicado: (2023)

Cross-calibration of pencil-beam (DPX-NT) and fan-beam (QDR-4500C) dual-energy X-ray absorptiometry for sarcopenia
por: Ito, Kenyu, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_6jf1g93m8it2n8u8ho4e984pnq