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De Novo Crescentic Glomerulonephritis Following COVID-19 Infection: A Pediatric Case Report

As the global coronavirus disease 2019 (COVID-19) pandemic continues to sweep across the globe, reports of kidney involvement in adult patients infected with COVID-19 have been documented, and recently, cases in the pediatric population have also been reported. This report highlights the case of an...

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Autores principales: Eun, Jung Kwan, Park, Min Ji, Kim, Mee-seon, Han, Man Hoon, Kim, Yong-Jin, Baek, Hee Sun, Cho, Min Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042728/
https://www.ncbi.nlm.nih.gov/pubmed/36974398
http://dx.doi.org/10.3346/jkms.2023.38.e89
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author Eun, Jung Kwan
Park, Min Ji
Kim, Mee-seon
Han, Man Hoon
Kim, Yong-Jin
Baek, Hee Sun
Cho, Min Hyun
author_facet Eun, Jung Kwan
Park, Min Ji
Kim, Mee-seon
Han, Man Hoon
Kim, Yong-Jin
Baek, Hee Sun
Cho, Min Hyun
author_sort Eun, Jung Kwan
collection PubMed
description As the global coronavirus disease 2019 (COVID-19) pandemic continues to sweep across the globe, reports of kidney involvement in adult patients infected with COVID-19 have been documented, and recently, cases in the pediatric population have also been reported. This report highlights the case of an 11-year-old boy who developed acute kidney injury presenting as gross hematuria, proteinuria, and hypertension immediately after a COVID-19 infection. A renal biopsy allowed us to diagnose the patient with post-COVID-19 infection-associated de novo crescentic immune-mediated glomerulonephritis. Oral prednisolone and cyclophosphamide treatments were initiated after methylprednisolone pulse therapy administration. Currently, the patient is receiving medical treatment for five weeks, and his renal function is gradually recovering. Previous studies have suggested that, although quite rare, a variety of kidney complications can occur after COVID-19 infection or vaccination, and it is recommended to monitor renal function through evaluation. Herein, we report a pediatric case of post-COVID-19 infection-associated de novo crescentic immune-mediated glomerulonephritis consistent with rapidly progressive glomerulonephritis.
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spelling pubmed-100427282023-03-29 De Novo Crescentic Glomerulonephritis Following COVID-19 Infection: A Pediatric Case Report Eun, Jung Kwan Park, Min Ji Kim, Mee-seon Han, Man Hoon Kim, Yong-Jin Baek, Hee Sun Cho, Min Hyun J Korean Med Sci Case Report As the global coronavirus disease 2019 (COVID-19) pandemic continues to sweep across the globe, reports of kidney involvement in adult patients infected with COVID-19 have been documented, and recently, cases in the pediatric population have also been reported. This report highlights the case of an 11-year-old boy who developed acute kidney injury presenting as gross hematuria, proteinuria, and hypertension immediately after a COVID-19 infection. A renal biopsy allowed us to diagnose the patient with post-COVID-19 infection-associated de novo crescentic immune-mediated glomerulonephritis. Oral prednisolone and cyclophosphamide treatments were initiated after methylprednisolone pulse therapy administration. Currently, the patient is receiving medical treatment for five weeks, and his renal function is gradually recovering. Previous studies have suggested that, although quite rare, a variety of kidney complications can occur after COVID-19 infection or vaccination, and it is recommended to monitor renal function through evaluation. Herein, we report a pediatric case of post-COVID-19 infection-associated de novo crescentic immune-mediated glomerulonephritis consistent with rapidly progressive glomerulonephritis. The Korean Academy of Medical Sciences 2023-03-08 /pmc/articles/PMC10042728/ /pubmed/36974398 http://dx.doi.org/10.3346/jkms.2023.38.e89 Text en © 2023 The Korean Academy of Medical Sciences. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Eun, Jung Kwan
Park, Min Ji
Kim, Mee-seon
Han, Man Hoon
Kim, Yong-Jin
Baek, Hee Sun
Cho, Min Hyun
De Novo Crescentic Glomerulonephritis Following COVID-19 Infection: A Pediatric Case Report
title De Novo Crescentic Glomerulonephritis Following COVID-19 Infection: A Pediatric Case Report
title_full De Novo Crescentic Glomerulonephritis Following COVID-19 Infection: A Pediatric Case Report
title_fullStr De Novo Crescentic Glomerulonephritis Following COVID-19 Infection: A Pediatric Case Report
title_full_unstemmed De Novo Crescentic Glomerulonephritis Following COVID-19 Infection: A Pediatric Case Report
title_short De Novo Crescentic Glomerulonephritis Following COVID-19 Infection: A Pediatric Case Report
title_sort de novo crescentic glomerulonephritis following covid-19 infection: a pediatric case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042728/
https://www.ncbi.nlm.nih.gov/pubmed/36974398
http://dx.doi.org/10.3346/jkms.2023.38.e89
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