Cargando…

Genetic risk of depression is different in subgroups of dietary ratio of tryptophan to large neutral amino acids

Manipulation of intake of serotonin precursor tryptophan has been exploited to rapidly induce and alleviate depression symptoms. While studies show that this latter effect is dependent on genetic vulnerability to depression, the effect of habitual tryptophan intake in the context of predisposing gen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bruncsics, Bence, Hullam, Gabor, Bolgar, Bence, Petschner, Peter, Millinghoffer, Andras, Gecse, Kinga, Eszlari, Nora, Gonda, Xenia, Jones, Debra J., Burden, Sorrel T., Antal, Peter, Deakin, Bill, Bagdy, Gyorgy, Juhasz, Gabriella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042855/ https://www.ncbi.nlm.nih.gov/pubmed/36973313 http://dx.doi.org/10.1038/s41598-023-31495-x

Ejemplares similares

Biology of Perseverative Negative Thinking: The Role of Timing and Folate Intake
por: Eszlari, Nora, et al.
Publicado: (2021)

Genetic effects on educational attainment in Hungary
por: Ujma, Péter P., et al.
Publicado: (2021)

The UKB envirome of depression: from interactions to synergistic effects
por: Hullam, Gabor, et al.
Publicado: (2019)

Comorbidities in the diseasome are more apparent than real: What Bayesian filtering reveals about the comorbidities of depression
por: Marx, Peter, et al.
Publicado: (2017)

Significance of risk polymorphisms for depression depends on stress exposure
por: Gonda, Xenia, et al.
Publicado: (2018)

Genome-wide association analysis reveals KCTD12 and miR-383-binding genes in the background of rumination
por: Eszlari, Nora, et al.
Publicado: (2019)

Genetic underpinnings of affective temperaments: a pilot GWAS investigation identifies a new genome-wide significant SNP for anxious temperament in ADGRB3 gene
por: Gonda, Xenia, et al.
Publicado: (2021)

A replication study separates polymorphisms behind migraine with and without depression
por: Petschner, Peter, et al.
Publicado: (2021)

Inflammation and Blood-Brain Barrier in Depression: Interaction of CLDN5 and IL6 Gene Variants in Stress-Induced Depression
por: Gal, Zsofia, et al.
Publicado: (2022)

A new stress sensor and risk factor for suicide: the T allele of the functional genetic variant in the GABRA6 gene
por: Gonda, Xenia, et al.
Publicado: (2017)

Variability in the Effect of 5-HTTLPR on Depression in a Large European Population: The Role of Age, Symptom Profile, Type and Intensity of Life Stressors
por: Juhasz, Gabriella, et al.
Publicado: (2015)

Effects of Different Stressors Are Modulated by Different Neurobiological Systems: The Role of GABA-A Versus CB1 Receptor Gene Variants in Anxiety and Depression
por: Gonda, Xenia, et al.
Publicado: (2019)

Antidepressant treatment response is modulated by genetic and environmental factors and their interactions
por: Kovacs, Dávid, et al.
Publicado: (2014)

Financial Stress Interacts With CLOCK Gene to Affect Migraine
por: Baksa, Daniel, et al.
Publicado: (2020)

Childhood Adversity Moderates the Effects of HTR2A Epigenetic Regulatory Polymorphisms on Rumination
por: Eszlari, Nora, et al.
Publicado: (2019)

“Out, out, brief candle! Life’s but a walking shadow”: 5-HTTLPR Is Associated With Current Suicidal Ideation but Not With Previous Suicide Attempts and Interacts With Recent Relationship Problems
por: Bokor, Janos, et al.
Publicado: (2020)

Catenin Alpha 2 May Be a Biomarker or Potential Drug Target in Psychiatric Disorders with Perseverative Negative Thinking
por: Eszlari, Nora, et al.
Publicado: (2021)

Interleukin-6 promoter polymorphism interacts with pain and life stress influencing depression phenotypes
por: Kovacs, David, et al.
Publicado: (2016)

The Genetic Underpinnings of Affective Temperaments: Identifying Novel Risk Variants with a Whole Genome Analytical Approach
por: Gonda, X., et al.
Publicado: (2022)

Inflamed Mind: Multiple Genetic Variants of IL6 Influence Suicide Risk Phenotypes in Interaction With Early and Recent Adversities in a Linkage Disequilibrium-Based Clumping Analysis
por: Bokor, Janos, et al.
Publicado: (2021)

Every Night and Every Morn: Effect of Variation in CLOCK Gene on Depression Depends on Exposure to Early and Recent Stress
por: Gyorik, Dorka, et al.
Publicado: (2021)

P2RX7 gene variation mediates the effect of childhood adversity and recent stress on the severity of depressive symptoms
por: Kristof, Zsuliet, et al.
Publicado: (2021)

“… wise, amazed, temp’rate, and furious, Loyal and neutral, in a moment”: first heritability analysis of affective temperaments reports remarkably high SNP-based heritability
por: Gonda, X., et al.
Publicado: (2023)

Variation along P2RX7 interacts with early traumas on severity of anxiety suggesting a role for neuroinflammation
por: Kristof, Zsuliet, et al.
Publicado: (2023)

VB-MK-LMF: fusion of drugs, targets and interactions using variational Bayesian multiple kernel logistic matrix factorization
por: Bolgár, Bence, et al.
Publicado: (2017)

Association of genetic variants of Glutamate Metabotropic Receptor 5 gene and state-anhedonia
por: Török, D., et al.
Publicado: (2022)

Body mass index and depressive rumination are positively associated with each other only in case of GG genotype of catenin alpha 2 gene rs13412541 variant
por: Eszlari, N., et al.
Publicado: (2022)

Nature and Nurture: Effects of Affective Temperaments on Depressive Symptoms Are Markedly Modified by Stress Exposure
por: Gonda, Xenia, et al.
Publicado: (2020)

Distinct effects of folate pathway genes MTHFR and MTHFD1L on ruminative response style: a potential risk mechanism for depression
por: Eszlari, N, et al.
Publicado: (2016)

VariantMetaCaller: automated fusion of variant calling pipelines for quantitative, precision-based filtering
por: Gézsi, András, et al.
Publicado: (2015)

Variants in the CNR1 gene predispose to headache with nausea in the presence of life stress
por: Juhasz, G., et al.
Publicado: (2016)

Association of ATP6V1B2 rs1106634 with lifetime risk of depression and hippocampal neurocognitive deficits: possible novel mechanisms in the etiopathology of depression
por: Gonda, X, et al.
Publicado: (2016)

Financial difficulties but not other types of recent negative life events show strong interactions with 5-HTTLPR genotype in the development of depressive symptoms
por: Gonda, X, et al.
Publicado: (2016)

Citalopram Neuroendocrine Challenge Shows Altered Tryptophan and Kynurenine Metabolism in Migraine
por: Gecse, Kinga, et al.
Publicado: (2022)

Downregulation of the Vitamin D Receptor Regulated Gene Set in the Hippocampus After MDMA Treatment
por: Petschner, Peter, et al.
Publicado: (2018)

Association of plasma tryptophan concentration with periaqueductal gray matter functional connectivity in migraine patients
por: Gecse, Kinga, et al.
Publicado: (2022)

How possible is the development of an operational psychometric method to assess the presence of the 5-HTTLPR s allele? Equivocal preliminary findings
por: Gonda, Xenia, et al.
Publicado: (2010)

Affective temperament polygenic risk scores predict depression: investigating the role of environmental factors
por: Győrik, D., et al.
Publicado: (2023)

MVsim: a toolset for quantifying and designing multivalent interactions
por: Bruncsics, Bence, et al.
Publicado: (2021)

MVsim is a toolset for quantifying and designing multivalent interactions
por: Bruncsics, Bence, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3evgu4339lilam9ie36drmd1tp