Determination of the Optimal Single Dose Treatment for Acoziborole, a Novel Drug for the Treatment of Human African Trypanosomiasis: First-in-Human Study

BACKGROUND AND OBJECTIVES: Acoziborole is a novel boron-containing candidate developed as an oral drug for the treatment of human African trypanosomiasis (HAT). Results from preclinical studies allowed progression to Phase 1 trials. We aimed to determine the best dose regimen for all stages of HAT....

Descripción completa

Detalles Bibliográficos
Autores principales: Tarral, Antoine, Hovsepian, Lionel, Duvauchelle, Thierry, Donazzolo, Yves, Latreille, Mathilde, Felices, Mathieu, Gualano, Virginie, Delhomme, Sophie, Valverde Mordt, Olaf, Blesson, Severine, Voiriot, Pascal, Strub-Wourgaft, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042906/
https://www.ncbi.nlm.nih.gov/pubmed/36763327
http://dx.doi.org/10.1007/s40262-023-01216-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042906/
https://www.ncbi.nlm.nih.gov/pubmed/36763327
http://dx.doi.org/10.1007/s40262-023-01216-8

Ejemplares similares