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Ergebnisse eines monozentrischen Gefäßscreeningprogramms in Deutschland

BACKGROUND: Cardiovascular diseases are the main cause of death in Europe with a relevant socioeconomic burden. A screening program for vascular diseases in asymptomatic persons with a defined risk constellation can lead to an early diagnosis. OBJECTIVE: The study examined a screening program for ca...

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Autores principales: Passek, K., Ronellenfitsch, U., Meisenbacher, K., Peters, A., Böckler, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042912/
https://www.ncbi.nlm.nih.gov/pubmed/36808496
http://dx.doi.org/10.1007/s00104-023-01821-0
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author Passek, K.
Ronellenfitsch, U.
Meisenbacher, K.
Peters, A.
Böckler, D.
author_facet Passek, K.
Ronellenfitsch, U.
Meisenbacher, K.
Peters, A.
Böckler, D.
author_sort Passek, K.
collection PubMed
description BACKGROUND: Cardiovascular diseases are the main cause of death in Europe with a relevant socioeconomic burden. A screening program for vascular diseases in asymptomatic persons with a defined risk constellation can lead to an early diagnosis. OBJECTIVE: The study examined a screening program for carotid stenosis, peripheral arterial occlusive disease (PAOD) and abdominal aortic aneurysms (AAA) in persons without any known vascular disease with respect to demographic data, risk factors, pre-existing conditions, medication intake, detection of pathological findings and/or findings requiring treatment. MATERIAL AND METHODS: Test subjects were invited using various information material and filled in a questionnaire on cardiovascular risk factors. The screening took place with measurement of the ABI and duplex sonography as a monocentric prospective single arm study within 1 year. Endpoints were the prevalence of risk factors and pathological and/or results requiring treatment. RESULTS: A total of 391 persons participated, 36% presented with at least 1 cardiovascular risk factor, 35.5% with 2 and 14.4% with 3 or more. The sonography showed results requiring control with a carotid stenosis of < 50–> 75% or occlusion in 9%. An AAA with a diameter of 3.0–4.5 cm was diagnosed in 0.9% and a pathological ABI < 0.9 or > 1.3 in 12.3%. The indications for a pharmacotherapy were found in 17% and no operation was recommended. CONCLUSION: The practicability of a screening program for carotid stenosis, PAOD and AAA of a defined risk population was shown. Vascular pathologies that required treatment were hardly found in the catchment area of the hospital. Consequently, the implementation of this screening program in Germany based on the collected data cannot currently be recommended in this form.
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spelling pubmed-100429122023-03-29 Ergebnisse eines monozentrischen Gefäßscreeningprogramms in Deutschland Passek, K. Ronellenfitsch, U. Meisenbacher, K. Peters, A. Böckler, D. Chirurgie (Heidelb) Originalien BACKGROUND: Cardiovascular diseases are the main cause of death in Europe with a relevant socioeconomic burden. A screening program for vascular diseases in asymptomatic persons with a defined risk constellation can lead to an early diagnosis. OBJECTIVE: The study examined a screening program for carotid stenosis, peripheral arterial occlusive disease (PAOD) and abdominal aortic aneurysms (AAA) in persons without any known vascular disease with respect to demographic data, risk factors, pre-existing conditions, medication intake, detection of pathological findings and/or findings requiring treatment. MATERIAL AND METHODS: Test subjects were invited using various information material and filled in a questionnaire on cardiovascular risk factors. The screening took place with measurement of the ABI and duplex sonography as a monocentric prospective single arm study within 1 year. Endpoints were the prevalence of risk factors and pathological and/or results requiring treatment. RESULTS: A total of 391 persons participated, 36% presented with at least 1 cardiovascular risk factor, 35.5% with 2 and 14.4% with 3 or more. The sonography showed results requiring control with a carotid stenosis of < 50–> 75% or occlusion in 9%. An AAA with a diameter of 3.0–4.5 cm was diagnosed in 0.9% and a pathological ABI < 0.9 or > 1.3 in 12.3%. The indications for a pharmacotherapy were found in 17% and no operation was recommended. CONCLUSION: The practicability of a screening program for carotid stenosis, PAOD and AAA of a defined risk population was shown. Vascular pathologies that required treatment were hardly found in the catchment area of the hospital. Consequently, the implementation of this screening program in Germany based on the collected data cannot currently be recommended in this form. Springer Medizin 2023-02-20 2023 /pmc/articles/PMC10042912/ /pubmed/36808496 http://dx.doi.org/10.1007/s00104-023-01821-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access Dieser Artikel wird unter der Creative Commons Namensnennung 4.0 International Lizenz veröffentlicht, welche die Nutzung, Vervielfältigung, Bearbeitung, Verbreitung und Wiedergabe in jeglichem Medium und Format erlaubt, sofern Sie den/die ursprünglichen Autor(en) und die Quelle ordnungsgemäß nennen, einen Link zur Creative Commons Lizenz beifügen und angeben, ob Änderungen vorgenommen wurden. Die in diesem Artikel enthaltenen Bilder und sonstiges Drittmaterial unterliegen ebenfalls der genannten Creative Commons Lizenz, sofern sich aus der Abbildungslegende nichts anderes ergibt. Sofern das betreffende Material nicht unter der genannten Creative Commons Lizenz steht und die betreffende Handlung nicht nach gesetzlichen Vorschriften erlaubt ist, ist für die oben aufgeführten Weiterverwendungen des Materials die Einwilligung des jeweiligen Rechteinhabers einzuholen. Weitere Details zur Lizenz entnehmen Sie bitte der Lizenzinformation auf http://creativecommons.org/licenses/by/4.0/deed.de (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Originalien
Passek, K.
Ronellenfitsch, U.
Meisenbacher, K.
Peters, A.
Böckler, D.
Ergebnisse eines monozentrischen Gefäßscreeningprogramms in Deutschland
title Ergebnisse eines monozentrischen Gefäßscreeningprogramms in Deutschland
title_full Ergebnisse eines monozentrischen Gefäßscreeningprogramms in Deutschland
title_fullStr Ergebnisse eines monozentrischen Gefäßscreeningprogramms in Deutschland
title_full_unstemmed Ergebnisse eines monozentrischen Gefäßscreeningprogramms in Deutschland
title_short Ergebnisse eines monozentrischen Gefäßscreeningprogramms in Deutschland
title_sort ergebnisse eines monozentrischen gefäßscreeningprogramms in deutschland
topic Originalien
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042912/
https://www.ncbi.nlm.nih.gov/pubmed/36808496
http://dx.doi.org/10.1007/s00104-023-01821-0
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