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PARP1 Gene Knockout Suppresses Expression of DNA Base Excision Repair Genes

The effect of PARP1 knockout in HEK293 cells on the gene expression of DNA base excision repair (BER) proteins was studied. It was shown that the expression of all differentially expressed genes (DEGs) of BER was reduced by knockout. The expression of the DNA glycosylase gene NEIL1, which is conside...

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Detalles Bibliográficos
Autores principales:	Zakharenko, A. L., Malakhova, A. A., Dyrkheeva, N. S., Okorokova, L. S., Medvedev, S. P., Zakian, S. M., Kabilov, M. R., Tupikin, A. A., Lavrik, O. I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pleiades Publishing 2023
Materias:	Biochemistry, Biophysics, and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042944/ https://www.ncbi.nlm.nih.gov/pubmed/36653586 http://dx.doi.org/10.1134/S1607672922700028

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