Structural insights into the human niacin receptor HCA2-G(i) signalling complex

The hydroxycarboxylic acid receptor 2 (HCA2) agonist niacin has been used as treatment for dyslipidemia for several decades albeit with skin flushing as a common side-effect in treated individuals. Extensive efforts have been made to identify HCA2 targeting lipid lowering agents with fewer adverse e...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Yang, Kang, Hye Jin, Gao, Ruogu, Wang, Jingjing, Han, Gye Won, DiBerto, Jeffrey F., Wu, Lijie, Tong, Jiahui, Qu, Lu, Wu, Yiran, Pileski, Ryan, Li, Xuemei, Zhang, Xuejun Cai, Zhao, Suwen, Kenakin, Terry, Wang, Quan, Stevens, Raymond C., Peng, Wei, Roth, Bryan L., Rao, Zihe, Liu, Zhi-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043007/
https://www.ncbi.nlm.nih.gov/pubmed/36973264
http://dx.doi.org/10.1038/s41467-023-37177-6

Ejemplares similares

Ejemplares similares