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A Probabilistic Cost-Effectiveness Analysis of Venetoclax and Obinutuzumab as a First-Line Therapy in Chronic Lymphocytic Leukemia in Canada
BACKGROUND: Venetoclax is a first-in-class targeted therapy option that is an inducer of apoptosis in chronic lymphocytic leukemia (CLL) cells. The open-label phase III CLL14 clinical trial showed that venetoclax combined with obinutuzumab (VEN+O) is superior to obinutuzumab combined with chlorambuc...
Autores principales: | Chatterjee, Anuja, van de Wetering, Gijs, Goeree, Ron, Owen, Carolyn, Desbois, Anne Marie, Barakat, Stephane, Manzoor, Beenish S., Sail, Kavita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043091/ https://www.ncbi.nlm.nih.gov/pubmed/36334238 http://dx.doi.org/10.1007/s41669-022-00375-x |
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