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Transmission of stimulus-induced epigenetic changes through cell division is coupled to continuous transcription factor activity
Trained immunity, or innate immune memory, has been attributed to the long-term retention of stimulus-induced histone post-translational modifications (PTMs) following clearance of the initial stimulus. Yet, it remains unknown how this epigenetic memory can persist for months in dividing cells given...
Autores principales: | Sun, Sarah, Aguirre-Gamboa, Raúl, Barreiro, Luis B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043173/ https://www.ncbi.nlm.nih.gov/pubmed/36999024 http://dx.doi.org/10.3389/fimmu.2023.1129577 |
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