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Transmission of stimulus-induced epigenetic changes through cell division is coupled to continuous transcription factor activity

Trained immunity, or innate immune memory, has been attributed to the long-term retention of stimulus-induced histone post-translational modifications (PTMs) following clearance of the initial stimulus. Yet, it remains unknown how this epigenetic memory can persist for months in dividing cells given...

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Detalles Bibliográficos
Autores principales: Sun, Sarah, Aguirre-Gamboa, Raúl, Barreiro, Luis B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043173/
https://www.ncbi.nlm.nih.gov/pubmed/36999024
http://dx.doi.org/10.3389/fimmu.2023.1129577

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