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Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model

As one of the most common diseases in pediatric surgery, an inguinal hernia is usually diagnosed by medical experts based on clinical data collected from magnetic resonance imaging (MRI), computed tomography (CT), or B-ultrasound. The parameters of blood routine examination, such as white blood cell...

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Autores principales: Liu, Zhi-Wen, Chen, Gang, Dong, Chao-Fan, Qiu, Wang-Ren, Zhang, Shou-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043203/
https://www.ncbi.nlm.nih.gov/pubmed/36998990
http://dx.doi.org/10.3389/fphys.2023.1105891
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author Liu, Zhi-Wen
Chen, Gang
Dong, Chao-Fan
Qiu, Wang-Ren
Zhang, Shou-Hua
author_facet Liu, Zhi-Wen
Chen, Gang
Dong, Chao-Fan
Qiu, Wang-Ren
Zhang, Shou-Hua
author_sort Liu, Zhi-Wen
collection PubMed
description As one of the most common diseases in pediatric surgery, an inguinal hernia is usually diagnosed by medical experts based on clinical data collected from magnetic resonance imaging (MRI), computed tomography (CT), or B-ultrasound. The parameters of blood routine examination, such as white blood cell count and platelet count, are often used as diagnostic indicators of intestinal necrosis. Based on the medical numerical data on blood routine examination parameters and liver and kidney function parameters, this paper used machine learning algorithm to assist the diagnosis of intestinal necrosis in children with inguinal hernia before operation. In the work, we used clinical data consisting of 3,807 children with inguinal hernia symptoms and 170 children with intestinal necrosis and perforation caused by the disease. Three different models were constructed according to the blood routine examination and liver and kidney function. Some missing values were replaced by using the RIN-3M (median, mean, or mode region random interpolation) method according to the actual necessity, and the ensemble learning based on the voting principle was used to deal with the imbalanced datasets. The model trained after feature selection yielded satisfactory results with an accuracy of 86.43%, sensitivity of 84.34%, specificity of 96.89%, and AUC value of 0.91. Therefore, the proposed methods may be a potential idea for auxiliary diagnosis of inguinal hernia in children.
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spelling pubmed-100432032023-03-29 Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model Liu, Zhi-Wen Chen, Gang Dong, Chao-Fan Qiu, Wang-Ren Zhang, Shou-Hua Front Physiol Physiology As one of the most common diseases in pediatric surgery, an inguinal hernia is usually diagnosed by medical experts based on clinical data collected from magnetic resonance imaging (MRI), computed tomography (CT), or B-ultrasound. The parameters of blood routine examination, such as white blood cell count and platelet count, are often used as diagnostic indicators of intestinal necrosis. Based on the medical numerical data on blood routine examination parameters and liver and kidney function parameters, this paper used machine learning algorithm to assist the diagnosis of intestinal necrosis in children with inguinal hernia before operation. In the work, we used clinical data consisting of 3,807 children with inguinal hernia symptoms and 170 children with intestinal necrosis and perforation caused by the disease. Three different models were constructed according to the blood routine examination and liver and kidney function. Some missing values were replaced by using the RIN-3M (median, mean, or mode region random interpolation) method according to the actual necessity, and the ensemble learning based on the voting principle was used to deal with the imbalanced datasets. The model trained after feature selection yielded satisfactory results with an accuracy of 86.43%, sensitivity of 84.34%, specificity of 96.89%, and AUC value of 0.91. Therefore, the proposed methods may be a potential idea for auxiliary diagnosis of inguinal hernia in children. Frontiers Media S.A. 2023-03-14 /pmc/articles/PMC10043203/ /pubmed/36998990 http://dx.doi.org/10.3389/fphys.2023.1105891 Text en Copyright © 2023 Liu, Chen, Dong, Qiu and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Liu, Zhi-Wen
Chen, Gang
Dong, Chao-Fan
Qiu, Wang-Ren
Zhang, Shou-Hua
Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model
title Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model
title_full Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model
title_fullStr Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model
title_full_unstemmed Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model
title_short Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model
title_sort intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043203/
https://www.ncbi.nlm.nih.gov/pubmed/36998990
http://dx.doi.org/10.3389/fphys.2023.1105891
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