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Structure-function relationships in the sodium chloride cotransporter
The thiazide sensitive Na(+):Cl(−) cotransporter (NCC) is the principal via for salt reabsorption in the apical membrane of the distal convoluted tubule (DCT) in mammals and plays a fundamental role in managing blood pressure. The cotransporter is targeted by thiazide diuretics, a highly prescribed...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043231/ https://www.ncbi.nlm.nih.gov/pubmed/36998989 http://dx.doi.org/10.3389/fphys.2023.1118706 |