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Structure-function relationships in the sodium chloride cotransporter

The thiazide sensitive Na(+):Cl(−) cotransporter (NCC) is the principal via for salt reabsorption in the apical membrane of the distal convoluted tubule (DCT) in mammals and plays a fundamental role in managing blood pressure. The cotransporter is targeted by thiazide diuretics, a highly prescribed...

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Detalles Bibliográficos
Autores principales: Moreno, Erika, Pacheco-Alvarez, Diana, Chávez-Canales, María, Elizalde, Stephanie, Leyva-Ríos, Karla, Gamba, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043231/
https://www.ncbi.nlm.nih.gov/pubmed/36998989
http://dx.doi.org/10.3389/fphys.2023.1118706