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Ergothioneine, a dietary antioxidant improves amyloid beta clearance in the neuroretina of a mouse model of Alzheimer’s disease

INTRODUCTION: Ergothioneine (Ergo) is a naturally occurring dietary antioxidant. Ergo uptake is dependent on the transporter, organic cation transporter novel-type 1 (OCTN1) distribution. OCTN1 is highly expressed in blood cells (myeloid lineage cells), brain and ocular tissues that are likely predi...

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Detalles Bibliográficos
Autores principales: Wijesinghe, Printha, Whitmore, Clayton A., Campbell, Matthew, Li, Charles, Tsuyuki, Miranda, To, Eleanor, Haynes, Justin, Pham, Wellington, Matsubara, Joanne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043244/
https://www.ncbi.nlm.nih.gov/pubmed/36998724
http://dx.doi.org/10.3389/fnins.2023.1107436

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