Time-of-day defines NAD(+) efficacy to treat diet-induced metabolic disease by synchronizing the hepatic clock in mice

The circadian clock is an endogenous time-tracking system that anticipates daily environmental changes. Misalignment of the clock can cause obesity, which is accompanied by reduced levels of the clock-controlled, rhythmic metabolite NAD(+). Increasing NAD(+) is becoming a therapy for metabolic dysfu...

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Detalles Bibliográficos
Autores principales: Escalante-Covarrubias, Quetzalcoatl, Mendoza-Viveros, Lucía, González-Suárez, Mirna, Sitten-Olea, Román, Velázquez-Villegas, Laura A., Becerril-Pérez, Fernando, Pacheco-Bernal, Ignacio, Carreño-Vázquez, Erick, Mass-Sánchez, Paola, Bustamante-Zepeda, Marcia, Orozco-Solís, Ricardo, Aguilar-Arnal, Lorena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043291/
https://www.ncbi.nlm.nih.gov/pubmed/36973248
http://dx.doi.org/10.1038/s41467-023-37286-2

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