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Multifactor dimensionality reduction method identifies novel SNP interactions in the WNT protein interaction networks that are associated with recurrence risk in colorectal cancer

BACKGROUND: Interactions among genetic variants are rarely studied but may explain a part of the variability in patient outcomes. OBJECTIVES: In this study, we aimed to identify 1 to 3 way interactions among SNPs from five Wnt protein interaction networks that predict the 5-year recurrence risk in a...

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Detalles Bibliográficos
Autores principales: Curtis, Aaron A., Yu, Yajun, Carey, Megan, Parfrey, Patrick, Yilmaz, Yildiz E., Savas, Sevtap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043327/
https://www.ncbi.nlm.nih.gov/pubmed/36998434
http://dx.doi.org/10.3389/fonc.2023.1122229