Cargando…

Deoxynivalenol in food and feed: Recent advances in decontamination strategies

Deoxynivalenol (DON) is a mycotoxin that contaminates animal feed and crops around the world. DON not only causes significant economic losses, but can also lead diarrhea, vomiting, and gastroenteritis in humans and farm animals. Thus, there is an urgent need to find efficient approaches for DON deco...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yingfeng, Gao, Huihui, Wang, Ru, Xu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043330/
https://www.ncbi.nlm.nih.gov/pubmed/36998392
http://dx.doi.org/10.3389/fmicb.2023.1141378
_version_ 1784913122411151360
author Li, Yingfeng
Gao, Huihui
Wang, Ru
Xu, Qing
author_facet Li, Yingfeng
Gao, Huihui
Wang, Ru
Xu, Qing
author_sort Li, Yingfeng
collection PubMed
description Deoxynivalenol (DON) is a mycotoxin that contaminates animal feed and crops around the world. DON not only causes significant economic losses, but can also lead diarrhea, vomiting, and gastroenteritis in humans and farm animals. Thus, there is an urgent need to find efficient approaches for DON decontamination in feed and food. However, physical and chemical treatment of DON may affect the nutrients, safety, and palatability of food. By contrast, biological detoxification methods based on microbial strains or enzymes have the advantages of high specificity, efficiency, and no secondary pollution. In this review, we comprehensively summarize the recently developed strategies for DON detoxification and classify their mechanisms. In addition, we identify remaining challenges in DON biodegradation and suggest research directions to address them. In the future, an in-depth understanding of the specific mechanisms through which DON is detoxified will provide an efficient, safe, and economical means for the removal of toxins from food and feed.
format Online
Article
Text
id pubmed-10043330
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-100433302023-03-29 Deoxynivalenol in food and feed: Recent advances in decontamination strategies Li, Yingfeng Gao, Huihui Wang, Ru Xu, Qing Front Microbiol Microbiology Deoxynivalenol (DON) is a mycotoxin that contaminates animal feed and crops around the world. DON not only causes significant economic losses, but can also lead diarrhea, vomiting, and gastroenteritis in humans and farm animals. Thus, there is an urgent need to find efficient approaches for DON decontamination in feed and food. However, physical and chemical treatment of DON may affect the nutrients, safety, and palatability of food. By contrast, biological detoxification methods based on microbial strains or enzymes have the advantages of high specificity, efficiency, and no secondary pollution. In this review, we comprehensively summarize the recently developed strategies for DON detoxification and classify their mechanisms. In addition, we identify remaining challenges in DON biodegradation and suggest research directions to address them. In the future, an in-depth understanding of the specific mechanisms through which DON is detoxified will provide an efficient, safe, and economical means for the removal of toxins from food and feed. Frontiers Media S.A. 2023-03-14 /pmc/articles/PMC10043330/ /pubmed/36998392 http://dx.doi.org/10.3389/fmicb.2023.1141378 Text en Copyright © 2023 Li, Gao, Wang and Xu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Li, Yingfeng
Gao, Huihui
Wang, Ru
Xu, Qing
Deoxynivalenol in food and feed: Recent advances in decontamination strategies
title Deoxynivalenol in food and feed: Recent advances in decontamination strategies
title_full Deoxynivalenol in food and feed: Recent advances in decontamination strategies
title_fullStr Deoxynivalenol in food and feed: Recent advances in decontamination strategies
title_full_unstemmed Deoxynivalenol in food and feed: Recent advances in decontamination strategies
title_short Deoxynivalenol in food and feed: Recent advances in decontamination strategies
title_sort deoxynivalenol in food and feed: recent advances in decontamination strategies
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043330/
https://www.ncbi.nlm.nih.gov/pubmed/36998392
http://dx.doi.org/10.3389/fmicb.2023.1141378
work_keys_str_mv AT liyingfeng deoxynivalenolinfoodandfeedrecentadvancesindecontaminationstrategies
AT gaohuihui deoxynivalenolinfoodandfeedrecentadvancesindecontaminationstrategies
AT wangru deoxynivalenolinfoodandfeedrecentadvancesindecontaminationstrategies
AT xuqing deoxynivalenolinfoodandfeedrecentadvancesindecontaminationstrategies