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Preserving the rectus femoris and improving limb function after total femoral prosthesis replacement following resection of femoral malignant tumors

BACKGROUND: Current research is focused on the factors that influence the maintenance of limb function after total femoral replacement. This retrospective study investigated the difference in functional outcomes in patients with invasion of the rectus femoris vs. an intact rectus femoris that underw...

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Autores principales: Wu, Fan, Fang, Xiang, Yuan, Dechao, Xiong, Yan, Luo, Yi, Zhang, Wenli, Tu, Chongqi, Duan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043403/
https://www.ncbi.nlm.nih.gov/pubmed/36998467
http://dx.doi.org/10.3389/fonc.2023.1149342
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author Wu, Fan
Fang, Xiang
Yuan, Dechao
Xiong, Yan
Luo, Yi
Zhang, Wenli
Tu, Chongqi
Duan, Hong
author_facet Wu, Fan
Fang, Xiang
Yuan, Dechao
Xiong, Yan
Luo, Yi
Zhang, Wenli
Tu, Chongqi
Duan, Hong
author_sort Wu, Fan
collection PubMed
description BACKGROUND: Current research is focused on the factors that influence the maintenance of limb function after total femoral replacement. This retrospective study investigated the difference in functional outcomes in patients with invasion of the rectus femoris vs. an intact rectus femoris that underwent total femoral replacement with a modular total femur prosthesis. METHODS: The medical records of patients who underwent total femoral replacement with a modular total femur prosthesis between July 2010 and March 2017 at our institute were retrospectively reviewed. The patients were divided into two groups: group A had invasion of the rectus femoris and group B had an intact rectus femoris. Functional status was assessed using the Musculoskeletal Tumor Society Rating Scale (MSTS) and the Harris Hip Score (HHS). Complications were assessed using the International Society of Limb Salvage classification that was published in 2011 and modified in 2014. RESULTS: The mean total MSTS score (23.0 ± 4.8 vs. 17.6 ± 3.1; P = 0.02) and the mean total HHS score (80.17 ± 6.24 vs. 55.38 ± 13.30; P = 0.001) were significantly higher in patients with intact rectus femoris compared with patients with invasion of the rectus femoris. Patients with an intact rectus femoris achieved significantly better limb function (support and gait) and active range of motion (P < 0.05). The overall complication rate was 35.7%. CONCLUSIONS: Functional outcomes after total femoral replacement were significantly better in patients with an intact rectus femoris compared with patients with invasion of the rectus femoris, possibly because more muscle mass can be preserved around the femur in patients with an intact rectus femoris.
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spelling pubmed-100434032023-03-29 Preserving the rectus femoris and improving limb function after total femoral prosthesis replacement following resection of femoral malignant tumors Wu, Fan Fang, Xiang Yuan, Dechao Xiong, Yan Luo, Yi Zhang, Wenli Tu, Chongqi Duan, Hong Front Oncol Oncology BACKGROUND: Current research is focused on the factors that influence the maintenance of limb function after total femoral replacement. This retrospective study investigated the difference in functional outcomes in patients with invasion of the rectus femoris vs. an intact rectus femoris that underwent total femoral replacement with a modular total femur prosthesis. METHODS: The medical records of patients who underwent total femoral replacement with a modular total femur prosthesis between July 2010 and March 2017 at our institute were retrospectively reviewed. The patients were divided into two groups: group A had invasion of the rectus femoris and group B had an intact rectus femoris. Functional status was assessed using the Musculoskeletal Tumor Society Rating Scale (MSTS) and the Harris Hip Score (HHS). Complications were assessed using the International Society of Limb Salvage classification that was published in 2011 and modified in 2014. RESULTS: The mean total MSTS score (23.0 ± 4.8 vs. 17.6 ± 3.1; P = 0.02) and the mean total HHS score (80.17 ± 6.24 vs. 55.38 ± 13.30; P = 0.001) were significantly higher in patients with intact rectus femoris compared with patients with invasion of the rectus femoris. Patients with an intact rectus femoris achieved significantly better limb function (support and gait) and active range of motion (P < 0.05). The overall complication rate was 35.7%. CONCLUSIONS: Functional outcomes after total femoral replacement were significantly better in patients with an intact rectus femoris compared with patients with invasion of the rectus femoris, possibly because more muscle mass can be preserved around the femur in patients with an intact rectus femoris. Frontiers Media S.A. 2023-03-14 /pmc/articles/PMC10043403/ /pubmed/36998467 http://dx.doi.org/10.3389/fonc.2023.1149342 Text en Copyright © 2023 Wu, Fang, Yuan, Xiong, Luo, Zhang, Tu and Duan https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Wu, Fan
Fang, Xiang
Yuan, Dechao
Xiong, Yan
Luo, Yi
Zhang, Wenli
Tu, Chongqi
Duan, Hong
Preserving the rectus femoris and improving limb function after total femoral prosthesis replacement following resection of femoral malignant tumors
title Preserving the rectus femoris and improving limb function after total femoral prosthesis replacement following resection of femoral malignant tumors
title_full Preserving the rectus femoris and improving limb function after total femoral prosthesis replacement following resection of femoral malignant tumors
title_fullStr Preserving the rectus femoris and improving limb function after total femoral prosthesis replacement following resection of femoral malignant tumors
title_full_unstemmed Preserving the rectus femoris and improving limb function after total femoral prosthesis replacement following resection of femoral malignant tumors
title_short Preserving the rectus femoris and improving limb function after total femoral prosthesis replacement following resection of femoral malignant tumors
title_sort preserving the rectus femoris and improving limb function after total femoral prosthesis replacement following resection of femoral malignant tumors
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043403/
https://www.ncbi.nlm.nih.gov/pubmed/36998467
http://dx.doi.org/10.3389/fonc.2023.1149342
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