Acute disseminated encephalomyelitis (ADEM)-like illness in a pediatric patient following COVID-19 vaccination

Since the inception of the COVID-19 pandemic, over 60 cases of acute disseminated encephalomyelitis (ADEM) or ADEM-like clinically isolated syndromes have been linked to COVID-19 infection. However, cases linked to COVID-19 vaccination remain exceptionally rare. To the author’s knowledge, eight publ...

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Autores principales: Brock, Kenneth, Reyes, Susana Creagh, Conner, Christopher, Gillson, Natalie, Weiss, Michael, Elfituri, Osama, Paydar, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043599/
https://www.ncbi.nlm.nih.gov/pubmed/36998331
http://dx.doi.org/10.1259/bjrcr.20220097
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author Brock, Kenneth
Reyes, Susana Creagh
Conner, Christopher
Gillson, Natalie
Weiss, Michael
Elfituri, Osama
Paydar, Amir
author_facet Brock, Kenneth
Reyes, Susana Creagh
Conner, Christopher
Gillson, Natalie
Weiss, Michael
Elfituri, Osama
Paydar, Amir
author_sort Brock, Kenneth
collection PubMed
description Since the inception of the COVID-19 pandemic, over 60 cases of acute disseminated encephalomyelitis (ADEM) or ADEM-like clinically isolated syndromes have been linked to COVID-19 infection. However, cases linked to COVID-19 vaccination remain exceptionally rare. To the author’s knowledge, eight published cases of ADEM or ADEM-like clinically isolated syndrome have been described after patients received COVID-19 vaccinations, all of which occurred in adults. This report details the first documented case of an ADEM-like illness in a pediatric patient, which developed shortly after receiving the Pfizer (Pfizer-BioNTech, Germany) COVID-19 vaccination. The patient made a near complete clinical recovery over 10 days after receiving a 5-day course of intravenous immunoglobulin therapy.
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spelling pubmed-100435992023-03-29 Acute disseminated encephalomyelitis (ADEM)-like illness in a pediatric patient following COVID-19 vaccination Brock, Kenneth Reyes, Susana Creagh Conner, Christopher Gillson, Natalie Weiss, Michael Elfituri, Osama Paydar, Amir BJR Case Rep Case Report Since the inception of the COVID-19 pandemic, over 60 cases of acute disseminated encephalomyelitis (ADEM) or ADEM-like clinically isolated syndromes have been linked to COVID-19 infection. However, cases linked to COVID-19 vaccination remain exceptionally rare. To the author’s knowledge, eight published cases of ADEM or ADEM-like clinically isolated syndrome have been described after patients received COVID-19 vaccinations, all of which occurred in adults. This report details the first documented case of an ADEM-like illness in a pediatric patient, which developed shortly after receiving the Pfizer (Pfizer-BioNTech, Germany) COVID-19 vaccination. The patient made a near complete clinical recovery over 10 days after receiving a 5-day course of intravenous immunoglobulin therapy. The British Institute of Radiology. 2023-02-20 /pmc/articles/PMC10043599/ /pubmed/36998331 http://dx.doi.org/10.1259/bjrcr.20220097 Text en © 2023 The Authors. Published by the British Institute of Radiology https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Brock, Kenneth
Reyes, Susana Creagh
Conner, Christopher
Gillson, Natalie
Weiss, Michael
Elfituri, Osama
Paydar, Amir
Acute disseminated encephalomyelitis (ADEM)-like illness in a pediatric patient following COVID-19 vaccination
title Acute disseminated encephalomyelitis (ADEM)-like illness in a pediatric patient following COVID-19 vaccination
title_full Acute disseminated encephalomyelitis (ADEM)-like illness in a pediatric patient following COVID-19 vaccination
title_fullStr Acute disseminated encephalomyelitis (ADEM)-like illness in a pediatric patient following COVID-19 vaccination
title_full_unstemmed Acute disseminated encephalomyelitis (ADEM)-like illness in a pediatric patient following COVID-19 vaccination
title_short Acute disseminated encephalomyelitis (ADEM)-like illness in a pediatric patient following COVID-19 vaccination
title_sort acute disseminated encephalomyelitis (adem)-like illness in a pediatric patient following covid-19 vaccination
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043599/
https://www.ncbi.nlm.nih.gov/pubmed/36998331
http://dx.doi.org/10.1259/bjrcr.20220097
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