Peroxisome proliferator-activated receptor ɣ agonist mediated inhibition of heparanase expression reduces proteinuria

BACKGROUND: Proteinuria is associated with many glomerular diseases and a risk factor for the progression to renal failure. We previously showed that heparanase (HPSE) is essential for the development of proteinuria, whereas peroxisome proliferator-activated receptor ɣ (PPARɣ) agonists can ameliorat...

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Detalles Bibliográficos
Autores principales: Garsen, Marjolein, Buijsers, Baranca, Sol, Marloes, Gockeln, Lena, Sonneveld, Ramon, van Kuppevelt, Toin H., de Graaf, Mark, van den Born, Jacob, Kamps, Jan A.A.M., van Raalte, Daniël H., van der Meer, Rutger W., Lamb, Hildo J., Hillebrands, Jan-Luuk, Rabelink, Ton J., Maciej-Hulme, Marissa L., Krenning, Guido, Nijenhuis, Tom, van der Vlag, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043778/
https://www.ncbi.nlm.nih.gov/pubmed/36889064
http://dx.doi.org/10.1016/j.ebiom.2023.104506

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