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Estimated Covid-19 burden in Spain: ARCH underreported non-stationary time series

BACKGROUND: The problem of dealing with misreported data is very common in a wide range of contexts for different reasons. The current situation caused by the Covid-19 worldwide pandemic is a clear example, where the data provided by official sources were not always reliable due to data collection i...

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Detalles Bibliográficos
Autores principales: Moriña, David, Fernández-Fontelo, Amanda, Cabaña, Alejandra, Arratia, Argimiro, Puig, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043853/
https://www.ncbi.nlm.nih.gov/pubmed/36977977
http://dx.doi.org/10.1186/s12874-023-01894-9
Descripción
Sumario:BACKGROUND: The problem of dealing with misreported data is very common in a wide range of contexts for different reasons. The current situation caused by the Covid-19 worldwide pandemic is a clear example, where the data provided by official sources were not always reliable due to data collection issues and to the high proportion of asymptomatic cases. In this work, a flexible framework is proposed, with the objective of quantifying the severity of misreporting in a time series and reconstructing the most likely evolution of the process. METHODS: The performance of Bayesian Synthetic Likelihood to estimate the parameters of a model based on AutoRegressive Conditional Heteroskedastic time series capable of dealing with misreported information and to reconstruct the most likely evolution of the phenomenon is assessed through a comprehensive simulation study and illustrated by reconstructing the weekly Covid-19 incidence in each Spanish Autonomous Community. RESULTS: Only around 51% of the Covid-19 cases in the period 2020/02/23–2022/02/27 were reported in Spain, showing relevant differences in the severity of underreporting across the regions. CONCLUSIONS: The proposed methodology provides public health decision-makers with a valuable tool in order to improve the assessment of a disease evolution under different scenarios. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12874-023-01894-9.