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Estimated Covid-19 burden in Spain: ARCH underreported non-stationary time series

BACKGROUND: The problem of dealing with misreported data is very common in a wide range of contexts for different reasons. The current situation caused by the Covid-19 worldwide pandemic is a clear example, where the data provided by official sources were not always reliable due to data collection i...

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Autores principales: Moriña, David, Fernández-Fontelo, Amanda, Cabaña, Alejandra, Arratia, Argimiro, Puig, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043853/
https://www.ncbi.nlm.nih.gov/pubmed/36977977
http://dx.doi.org/10.1186/s12874-023-01894-9
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author Moriña, David
Fernández-Fontelo, Amanda
Cabaña, Alejandra
Arratia, Argimiro
Puig, Pedro
author_facet Moriña, David
Fernández-Fontelo, Amanda
Cabaña, Alejandra
Arratia, Argimiro
Puig, Pedro
author_sort Moriña, David
collection PubMed
description BACKGROUND: The problem of dealing with misreported data is very common in a wide range of contexts for different reasons. The current situation caused by the Covid-19 worldwide pandemic is a clear example, where the data provided by official sources were not always reliable due to data collection issues and to the high proportion of asymptomatic cases. In this work, a flexible framework is proposed, with the objective of quantifying the severity of misreporting in a time series and reconstructing the most likely evolution of the process. METHODS: The performance of Bayesian Synthetic Likelihood to estimate the parameters of a model based on AutoRegressive Conditional Heteroskedastic time series capable of dealing with misreported information and to reconstruct the most likely evolution of the phenomenon is assessed through a comprehensive simulation study and illustrated by reconstructing the weekly Covid-19 incidence in each Spanish Autonomous Community. RESULTS: Only around 51% of the Covid-19 cases in the period 2020/02/23–2022/02/27 were reported in Spain, showing relevant differences in the severity of underreporting across the regions. CONCLUSIONS: The proposed methodology provides public health decision-makers with a valuable tool in order to improve the assessment of a disease evolution under different scenarios. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12874-023-01894-9.
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spelling pubmed-100438532023-03-28 Estimated Covid-19 burden in Spain: ARCH underreported non-stationary time series Moriña, David Fernández-Fontelo, Amanda Cabaña, Alejandra Arratia, Argimiro Puig, Pedro BMC Med Res Methodol Research BACKGROUND: The problem of dealing with misreported data is very common in a wide range of contexts for different reasons. The current situation caused by the Covid-19 worldwide pandemic is a clear example, where the data provided by official sources were not always reliable due to data collection issues and to the high proportion of asymptomatic cases. In this work, a flexible framework is proposed, with the objective of quantifying the severity of misreporting in a time series and reconstructing the most likely evolution of the process. METHODS: The performance of Bayesian Synthetic Likelihood to estimate the parameters of a model based on AutoRegressive Conditional Heteroskedastic time series capable of dealing with misreported information and to reconstruct the most likely evolution of the phenomenon is assessed through a comprehensive simulation study and illustrated by reconstructing the weekly Covid-19 incidence in each Spanish Autonomous Community. RESULTS: Only around 51% of the Covid-19 cases in the period 2020/02/23–2022/02/27 were reported in Spain, showing relevant differences in the severity of underreporting across the regions. CONCLUSIONS: The proposed methodology provides public health decision-makers with a valuable tool in order to improve the assessment of a disease evolution under different scenarios. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12874-023-01894-9. BioMed Central 2023-03-28 /pmc/articles/PMC10043853/ /pubmed/36977977 http://dx.doi.org/10.1186/s12874-023-01894-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Moriña, David
Fernández-Fontelo, Amanda
Cabaña, Alejandra
Arratia, Argimiro
Puig, Pedro
Estimated Covid-19 burden in Spain: ARCH underreported non-stationary time series
title Estimated Covid-19 burden in Spain: ARCH underreported non-stationary time series
title_full Estimated Covid-19 burden in Spain: ARCH underreported non-stationary time series
title_fullStr Estimated Covid-19 burden in Spain: ARCH underreported non-stationary time series
title_full_unstemmed Estimated Covid-19 burden in Spain: ARCH underreported non-stationary time series
title_short Estimated Covid-19 burden in Spain: ARCH underreported non-stationary time series
title_sort estimated covid-19 burden in spain: arch underreported non-stationary time series
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043853/
https://www.ncbi.nlm.nih.gov/pubmed/36977977
http://dx.doi.org/10.1186/s12874-023-01894-9
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