Progress towards a glycoconjugate vaccine against Group A Streptococcus

The Group A Carbohydrate (GAC) is a defining feature of Group A Streptococcus (Strep A) or Streptococcus pyogenes. It is a conserved and simple polysaccharide, comprising a rhamnose backbone and GlcNAc side chains, further decorated with glycerol phosphate on approximately 40% GlcNAc residues. Its c...

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Detalles Bibliográficos
Autores principales: Burns, Keira, Dorfmueller, Helge C., Wren, Brendan W., Mawas, Fatme, Shaw, Helen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043865/
https://www.ncbi.nlm.nih.gov/pubmed/36977677
http://dx.doi.org/10.1038/s41541-023-00639-5

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