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Setting Organ Allocation Priorities: A Discrete Choice Experiment with German Patients and Their Relatives
PURPOSE: Organ transplantation systems benefit from guidelines that are harmonious with the preferences of the people involved. Discrete choice experiments are useful tools for eliciting preferences. PATIENTS AND METHODS: This study evaluated the preferences of patients and their relatives (n=285) t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044066/ https://www.ncbi.nlm.nih.gov/pubmed/36999164 http://dx.doi.org/10.2147/PPA.S402203 |
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author | Bartling, Tim Oedingen, Carina Schrem, Harald Kohlmann, Thomas Krauth, Christian |
author_facet | Bartling, Tim Oedingen, Carina Schrem, Harald Kohlmann, Thomas Krauth, Christian |
author_sort | Bartling, Tim |
collection | PubMed |
description | PURPOSE: Organ transplantation systems benefit from guidelines that are harmonious with the preferences of the people involved. Discrete choice experiments are useful tools for eliciting preferences. PATIENTS AND METHODS: This study evaluated the preferences of patients and their relatives (n=285) to identify their priorities in organ allocation using a discrete choice experiment. In eight hypothetical allocation decisions, the participants were asked to select the candidate they considered the most suitable The candidates differed in years of life gained after transplantation, quality of life after transplantation, waiting time until transplantation, age, compliance and social support. RESULTS: The most important aspects for setting priority in organ allocation were lack of compliance (β= −2.5, p<0.001) and good quality of life after transplantation (β = +1.4, p<0.001). The lack of social support (ß = −0.8, p<0.05) and the more years of life gained after transplantation (β = +0.5, p<0.001) had less but still a significant amount of influence on this decision, while the waiting list was not considered significantly important (β = 0.1, p>0.05). The comparison of the different relations to transplantation showed that life years gained after transplantation was of high relevance to posttransplant patients (+10 years: β = +0.709, p<0.001 / +15 years: β = +0.700, p<0.001) and of no importance to waitlisted patients (+10 years: β = +0.345, p>0.05 / + 15 years: β = +0.173, p>0.05) and relatives (+ 10 years: β = +0.063, p>0.05 / +15 years: β = +0.304, p>0.05). CONCLUSION: This study provides useful insights into the unique perspective of patients and their relatives on priority-setting in the allocation of donor organs that should be reflected in improved donor organ allocation rules. |
format | Online Article Text |
id | pubmed-10044066 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-100440662023-03-29 Setting Organ Allocation Priorities: A Discrete Choice Experiment with German Patients and Their Relatives Bartling, Tim Oedingen, Carina Schrem, Harald Kohlmann, Thomas Krauth, Christian Patient Prefer Adherence Original Research PURPOSE: Organ transplantation systems benefit from guidelines that are harmonious with the preferences of the people involved. Discrete choice experiments are useful tools for eliciting preferences. PATIENTS AND METHODS: This study evaluated the preferences of patients and their relatives (n=285) to identify their priorities in organ allocation using a discrete choice experiment. In eight hypothetical allocation decisions, the participants were asked to select the candidate they considered the most suitable The candidates differed in years of life gained after transplantation, quality of life after transplantation, waiting time until transplantation, age, compliance and social support. RESULTS: The most important aspects for setting priority in organ allocation were lack of compliance (β= −2.5, p<0.001) and good quality of life after transplantation (β = +1.4, p<0.001). The lack of social support (ß = −0.8, p<0.05) and the more years of life gained after transplantation (β = +0.5, p<0.001) had less but still a significant amount of influence on this decision, while the waiting list was not considered significantly important (β = 0.1, p>0.05). The comparison of the different relations to transplantation showed that life years gained after transplantation was of high relevance to posttransplant patients (+10 years: β = +0.709, p<0.001 / +15 years: β = +0.700, p<0.001) and of no importance to waitlisted patients (+10 years: β = +0.345, p>0.05 / + 15 years: β = +0.173, p>0.05) and relatives (+ 10 years: β = +0.063, p>0.05 / +15 years: β = +0.304, p>0.05). CONCLUSION: This study provides useful insights into the unique perspective of patients and their relatives on priority-setting in the allocation of donor organs that should be reflected in improved donor organ allocation rules. Dove 2023-03-24 /pmc/articles/PMC10044066/ /pubmed/36999164 http://dx.doi.org/10.2147/PPA.S402203 Text en © 2023 Bartling et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Bartling, Tim Oedingen, Carina Schrem, Harald Kohlmann, Thomas Krauth, Christian Setting Organ Allocation Priorities: A Discrete Choice Experiment with German Patients and Their Relatives |
title | Setting Organ Allocation Priorities: A Discrete Choice Experiment with German Patients and Their Relatives |
title_full | Setting Organ Allocation Priorities: A Discrete Choice Experiment with German Patients and Their Relatives |
title_fullStr | Setting Organ Allocation Priorities: A Discrete Choice Experiment with German Patients and Their Relatives |
title_full_unstemmed | Setting Organ Allocation Priorities: A Discrete Choice Experiment with German Patients and Their Relatives |
title_short | Setting Organ Allocation Priorities: A Discrete Choice Experiment with German Patients and Their Relatives |
title_sort | setting organ allocation priorities: a discrete choice experiment with german patients and their relatives |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044066/ https://www.ncbi.nlm.nih.gov/pubmed/36999164 http://dx.doi.org/10.2147/PPA.S402203 |
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