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Hypoalbuminemia and Pharmacokinetics: When the Misunderstanding of a Fundamental Concept Leads to Repeated Errors over Decades

Surprisingly, misinterpretation of the influence of hypoalbuminemia on pharmacokinetics and the clinical effects of drugs seems to be a current problem, even though hypoalbuminemia has no impact on the pharmacologically active exposure. Exceptions to this fact are highly protein-bound anaesthetics w...

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Detalles Bibliográficos
Autores principales: Gandia, Peggy, Decheiver, Sarah, Picard, Manon, Guilhaumou, Romain, Baklouti, Sarah, Concordet, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044130/
https://www.ncbi.nlm.nih.gov/pubmed/36978382
http://dx.doi.org/10.3390/antibiotics12030515