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M1 polarization enhances the antitumor activity of chimeric antigen receptor macrophages in solid tumors
BACKGROUND: Chimeric antigen receptor macrophage (CAR-M) therapy is a novel cancer immunotherapy approach that integrates CAR structure and macrophage functions. CAR-M therapy has shown unique and impressive antitumor effects in immunotherapy for solid tumors. However, the polarization state of macr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044396/ https://www.ncbi.nlm.nih.gov/pubmed/36978075 http://dx.doi.org/10.1186/s12967-023-04061-2 |