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M1 polarization enhances the antitumor activity of chimeric antigen receptor macrophages in solid tumors

BACKGROUND: Chimeric antigen receptor macrophage (CAR-M) therapy is a novel cancer immunotherapy approach that integrates CAR structure and macrophage functions. CAR-M therapy has shown unique and impressive antitumor effects in immunotherapy for solid tumors. However, the polarization state of macr...

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Detalles Bibliográficos
Autores principales: Huo, Yi, Zhang, Han, Sa, Longqi, Zheng, Wenjing, He, Yang, Lyu, Haohan, Sun, Mengjie, Zhang, Lingling, Shan, Lequn, Yang, Angang, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044396/
https://www.ncbi.nlm.nih.gov/pubmed/36978075
http://dx.doi.org/10.1186/s12967-023-04061-2

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