Geographically weighted linear combination test for gene-set analysis of a continuous spatial phenotype as applied to intratumor heterogeneity

Background: The impact of gene-sets on a spatial phenotype is not necessarily uniform across different locations of cancer tissue. This study introduces a computational platform, GWLCT, for combining gene set analysis with spatial data modeling to provide a new statistical test for location-specific...

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Detalles Bibliográficos
Autores principales: Amini, Payam, Hajihosseini, Morteza, Pyne, Saumyadipta, Dinu, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044624/
https://www.ncbi.nlm.nih.gov/pubmed/36998245
http://dx.doi.org/10.3389/fcell.2023.1065586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044624/
https://www.ncbi.nlm.nih.gov/pubmed/36998245
http://dx.doi.org/10.3389/fcell.2023.1065586

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