Spatial and Temporal Protein Modules Signatures Associated with Alzheimer Disease in 3xTg-AD Mice Are Restored by Early Ubiquinol Supplementation

Despite its robust proteopathic nature, the spatiotemporal signature of disrupted protein modules in sporadic Alzheimer’s disease (AD) brains remains poorly understood. This considered oxidative stress contributes to AD progression and early intervention with coenzyme Q10 or its reduced form, ubiqui...

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Detalles Bibliográficos
Autores principales: Llanos-González, Emilio, Sancho-Bielsa, Francisco J., Frontiñán-Rubio, Javier, Rabanal-Ruíz, Yoana, García-Carpintero, Sonia, Chicano, Eduardo, Úbeda-Banon, Isabel, Flores-Cuadrado, Alicia, Giménez-Llort, Lydia, Alcaín, Francisco Javier, Peinado, Juan Ramón, Durán-Prado, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044705/
https://www.ncbi.nlm.nih.gov/pubmed/36978996
http://dx.doi.org/10.3390/antiox12030747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044705/
https://www.ncbi.nlm.nih.gov/pubmed/36978996
http://dx.doi.org/10.3390/antiox12030747

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