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Spatial and Temporal Protein Modules Signatures Associated with Alzheimer Disease in 3xTg-AD Mice Are Restored by Early Ubiquinol Supplementation
Despite its robust proteopathic nature, the spatiotemporal signature of disrupted protein modules in sporadic Alzheimer’s disease (AD) brains remains poorly understood. This considered oxidative stress contributes to AD progression and early intervention with coenzyme Q10 or its reduced form, ubiqui...
Autores principales: | Llanos-González, Emilio, Sancho-Bielsa, Francisco J., Frontiñán-Rubio, Javier, Rabanal-Ruíz, Yoana, García-Carpintero, Sonia, Chicano, Eduardo, Úbeda-Banon, Isabel, Flores-Cuadrado, Alicia, Giménez-Llort, Lydia, Alcaín, Francisco Javier, Peinado, Juan Ramón, Durán-Prado, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044705/ https://www.ncbi.nlm.nih.gov/pubmed/36978996 http://dx.doi.org/10.3390/antiox12030747 |
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