LCN2 secreted by tissue-infiltrating neutrophils induces the ferroptosis and wasting of adipose and muscle tissues in lung cancer cachexia

BACKGROUND: Cancer cachexia is a deadly wasting syndrome that accompanies various diseases (including ~ 50% of cancers). Clinical studies have established that cachexia is not a nutritional deficiency and is linked to expression of certain proteins (e.g., interleukin-6 and C-reactive protein), but m...

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Detalles Bibliográficos
Autores principales: Wang, Dong, Li, Xiaohui, Jiao, Defeng, Cai, Ying, Qian, Liting, Shen, Yiqing, Lu, Yichen, Zhou, Yonggang, Fu, Binqing, Sun, Rui, Tian, Zhigang, Zheng, Xiaohu, Wei, Haiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044814/
https://www.ncbi.nlm.nih.gov/pubmed/36973755
http://dx.doi.org/10.1186/s13045-023-01429-1

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