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GYY4137-Derived Hydrogen Sulfide Donates Electrons to the Mitochondrial Electron Transport Chain via Sulfide: Quinone Oxidoreductase in Endothelial Cells

The protective effects of hydrogen sulphide (H(2)S) to limit oxidative injury and preserve mitochondrial function during sepsis, ischemia/reperfusion, and neurodegenerative diseases have prompted the development of soluble H(2)S-releasing compounds such as GYY4137. Yet, the effects of GYY4137 on the...

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Detalles Bibliográficos
Autores principales: Star, Bastiaan S., van der Slikke, Elisabeth C., Ransy, Céline, Schmitt, Alain, Henning, Robert H., Bouillaud, Frédéric, Bouma, Hjalmar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044827/
https://www.ncbi.nlm.nih.gov/pubmed/36978834
http://dx.doi.org/10.3390/antiox12030587