Voltage-Gated Proton Channel Hv1 Regulates Neuroinflammation and Dopaminergic Neurodegeneration in Parkinson’s Disease Models

Although the precise mechanisms for neurodegeneration in Parkinson’s disease (PD) are unknown, evidence suggests that neuroinflammation is a critical factor in the pathogenic process. Here, we sought to determine whether the voltage-gated proton channel, Hv1 (HVCN1), which is expressed in microglia...

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Detalles Bibliográficos
Autores principales: Neal, Matthew L., Beier, Eric E., Hossain, Muhammad M., Boyle, Alexa, Zheng, Jiaying, Kim, Chunki, Mhatre-Winters, Isha, Wu, Long-Jun, Richardson, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044828/
https://www.ncbi.nlm.nih.gov/pubmed/36978830
http://dx.doi.org/10.3390/antiox12030582

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