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Nrf2 Activation Does Not Protect from Aldosterone-Induced Kidney Damage in Mice

Nuclear factor erythroid 2-related factor 2 (Nrf2) is downregulated in chronic kidney disease (CKD). Activation of Nrf2 might be a therapeutic option in CKD. Here we investigate the effect of Nrf2 activation on aldosterone (Aldo)-induced renal injury. Wild-type (WT) mice, transgenic Keap1 hypomorphi...

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Detalles Bibliográficos
Autores principales:	Brinks, Ronja, Wruck, Christoph Jan, Schmitz, Jutta, Schupp, Nicole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044832/ https://www.ncbi.nlm.nih.gov/pubmed/36979025 http://dx.doi.org/10.3390/antiox12030777

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