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Effect of Extracellular Matrix Stiffness on Candesartan Efficacy in Anti-Fibrosis and Antioxidation

Myocardial fibrosis progression and imbalanced redox state are closely associated with increased extracellular matrix (ECM) stiffness. Candesartan (CAN), an angiotensin II (Ang II) receptor inhibitor, has shown promising anti-fibrosis and antioxidant efficacy in previous cardiovascular disease studi...

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Detalles Bibliográficos
Autores principales: Zhu, Tong, Song, Jingjing, Gao, Bin, Zhang, Junjie, Li, Yabei, Ye, Zhaoyang, Zhao, Yuxiang, Guo, Xiaogang, Xu, Feng, Li, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044920/
https://www.ncbi.nlm.nih.gov/pubmed/36978927
http://dx.doi.org/10.3390/antiox12030679