Stimulation of Hepatic Ferritinophagy Mitigates Irp2 Depletion-Induced Anemia

Background: Iron regulatory proteins (IRPs) maintain cellular iron homeostasis. Due to aberrant tissue-iron distribution, Irp2-deficient mice suffer microcytic anemia and neurodegeneration, while iron overload occurs in the liver and intestine. We previously found that Irp2 deficiency-induced Hif2 p...

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Detalles Bibliográficos
Autores principales: Liu, Yutong, Li, Yuxuan, Yang, Liu, Shen, Jiaqi, Zhao, Hongting, Dong, Weichen, Chang, Yanzhong, Qiao, Tong, Li, Kuanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044941/
https://www.ncbi.nlm.nih.gov/pubmed/36978814
http://dx.doi.org/10.3390/antiox12030566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044941/
https://www.ncbi.nlm.nih.gov/pubmed/36978814
http://dx.doi.org/10.3390/antiox12030566

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