Cargando…
Stimulation of Hepatic Ferritinophagy Mitigates Irp2 Depletion-Induced Anemia
Background: Iron regulatory proteins (IRPs) maintain cellular iron homeostasis. Due to aberrant tissue-iron distribution, Irp2-deficient mice suffer microcytic anemia and neurodegeneration, while iron overload occurs in the liver and intestine. We previously found that Irp2 deficiency-induced Hif2 p...
Autores principales: | Liu, Yutong, Li, Yuxuan, Yang, Liu, Shen, Jiaqi, Zhao, Hongting, Dong, Weichen, Chang, Yanzhong, Qiao, Tong, Li, Kuanyu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044941/ https://www.ncbi.nlm.nih.gov/pubmed/36978814 http://dx.doi.org/10.3390/antiox12030566 |
Ejemplares similares
-
Protective Effects of Hif2 Inhibitor PT-2385 on a Neurological Disorder Induced by Deficiency of Irp2
por: Shen, Jiaqi, et al.
Publicado: (2021) -
Iron-dependent degradation of IRP2 requires its C-terminal region and IRP structural integrity
por: Wang, Jian, et al.
Publicado: (2008) -
Ferroptosis and ferritinophagy in diabetes complications
por: He, Jiahui, et al.
Publicado: (2022) -
Co‐regulation of hepatic steatosis by ferritinophagy and unsaturated fatty acid supply
por: Li, Ning, et al.
Publicado: (2022) -
The critical role of ferritinophagy in human disease
por: Liu, Meng-Zhen, et al.
Publicado: (2022)