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Examined lymph node count for gastric cancer patients after curative surgery

Lymph node (LN) metastasis is the most common form of metastasis in gastric cancer (GC). The status and stage of LN metastasis are important indicators that reflect the progress of GC. The number of LN metastases is still the most effective index to evaluate the prognosis of patients in all stages o...

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Autores principales: Zeng, Yi, Chen, Lu-Chuan, Ye, Zai-Sheng, Deng, Jing-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044965/
https://www.ncbi.nlm.nih.gov/pubmed/36998963
http://dx.doi.org/10.12998/wjcc.v11.i9.1930
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author Zeng, Yi
Chen, Lu-Chuan
Ye, Zai-Sheng
Deng, Jing-Yu
author_facet Zeng, Yi
Chen, Lu-Chuan
Ye, Zai-Sheng
Deng, Jing-Yu
author_sort Zeng, Yi
collection PubMed
description Lymph node (LN) metastasis is the most common form of metastasis in gastric cancer (GC). The status and stage of LN metastasis are important indicators that reflect the progress of GC. The number of LN metastases is still the most effective index to evaluate the prognosis of patients in all stages of LN metastasis. Examined LN (ELN) count refers to the number of LNs harvested from specimens by curative gastrectomy for pathological examination. This review summarizes the factors that influence ELN count, including individual and tumor factors, intraoperative dissection factors, postoperative sorting factors, and pathological examination factors. Different ELN counts will lead to prognosis-related stage migration. Fine LN sorting and regional LN sorting are the two most important LN sorting technologies. The most direct and effective way to harvest a large number of LNs is for surgeons to perform in vitro fine LN sorting.
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spelling pubmed-100449652023-03-29 Examined lymph node count for gastric cancer patients after curative surgery Zeng, Yi Chen, Lu-Chuan Ye, Zai-Sheng Deng, Jing-Yu World J Clin Cases Minireviews Lymph node (LN) metastasis is the most common form of metastasis in gastric cancer (GC). The status and stage of LN metastasis are important indicators that reflect the progress of GC. The number of LN metastases is still the most effective index to evaluate the prognosis of patients in all stages of LN metastasis. Examined LN (ELN) count refers to the number of LNs harvested from specimens by curative gastrectomy for pathological examination. This review summarizes the factors that influence ELN count, including individual and tumor factors, intraoperative dissection factors, postoperative sorting factors, and pathological examination factors. Different ELN counts will lead to prognosis-related stage migration. Fine LN sorting and regional LN sorting are the two most important LN sorting technologies. The most direct and effective way to harvest a large number of LNs is for surgeons to perform in vitro fine LN sorting. Baishideng Publishing Group Inc 2023-03-26 2023-03-26 /pmc/articles/PMC10044965/ /pubmed/36998963 http://dx.doi.org/10.12998/wjcc.v11.i9.1930 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Minireviews
Zeng, Yi
Chen, Lu-Chuan
Ye, Zai-Sheng
Deng, Jing-Yu
Examined lymph node count for gastric cancer patients after curative surgery
title Examined lymph node count for gastric cancer patients after curative surgery
title_full Examined lymph node count for gastric cancer patients after curative surgery
title_fullStr Examined lymph node count for gastric cancer patients after curative surgery
title_full_unstemmed Examined lymph node count for gastric cancer patients after curative surgery
title_short Examined lymph node count for gastric cancer patients after curative surgery
title_sort examined lymph node count for gastric cancer patients after curative surgery
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044965/
https://www.ncbi.nlm.nih.gov/pubmed/36998963
http://dx.doi.org/10.12998/wjcc.v11.i9.1930
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