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The effect of denosumab on disseminated tumor cells (DTCs) of breast cancer patients with neoadjuvant treatment: a GeparX translational substudy

BACKGROUND: Disseminated tumor cells (DTCs) in the bone marrow are observed in about 40% at primary diagnosis of breast cancer and predict poor survival. While anti-resorptive therapy with bisphosphonates was shown to eradicate minimal residue disease in the bone marrow, the effect of denosumab on D...

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Detalles Bibliográficos
Autores principales: Wimberger, Pauline, Blohmer, Jens-Uwe, Krabisch, Petra, Link, Theresa, Just, Marianne, Sinn, Bruno Valentin, Simon, Eike, Solbach, Christine, Fehm, Tanja, Denkert, Carsten, Kühn, Cristin, Rhiem, Kerstin, Tesch, Hans, Kümmel, Sherko, Petzold, Andrea, Stötzer, Oliver, Meisel, Cornelia, Kuhlmann, Jan Dominik, Nekljudova, Valentina, Loibl, Sibylle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045108/
https://www.ncbi.nlm.nih.gov/pubmed/36978142
http://dx.doi.org/10.1186/s13058-023-01619-2

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