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The effect of denosumab on disseminated tumor cells (DTCs) of breast cancer patients with neoadjuvant treatment: a GeparX translational substudy
BACKGROUND: Disseminated tumor cells (DTCs) in the bone marrow are observed in about 40% at primary diagnosis of breast cancer and predict poor survival. While anti-resorptive therapy with bisphosphonates was shown to eradicate minimal residue disease in the bone marrow, the effect of denosumab on D...
Autores principales: | Wimberger, Pauline, Blohmer, Jens-Uwe, Krabisch, Petra, Link, Theresa, Just, Marianne, Sinn, Bruno Valentin, Simon, Eike, Solbach, Christine, Fehm, Tanja, Denkert, Carsten, Kühn, Cristin, Rhiem, Kerstin, Tesch, Hans, Kümmel, Sherko, Petzold, Andrea, Stötzer, Oliver, Meisel, Cornelia, Kuhlmann, Jan Dominik, Nekljudova, Valentina, Loibl, Sibylle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045108/ https://www.ncbi.nlm.nih.gov/pubmed/36978142 http://dx.doi.org/10.1186/s13058-023-01619-2 |
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