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MRI Liver Imaging Integrated with Texture Analysis in Native Liver Survivor Patients with Biliary Atresia after Kasai Portoenterostomy: Correlation with Medical Outcome after Surgical Treatment
Kasai portoenterostomy (KP) plays a crucial role in the treatment of biliary atresia (BA). The aim is to correlate MRI quantitative findings of native liver survivor BA patients after KP with a medical outcome. Thirty patients were classified as having ideal medical outcomes (Group 1; n = 11) if lab...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045135/ https://www.ncbi.nlm.nih.gov/pubmed/36978697 http://dx.doi.org/10.3390/bioengineering10030306 |
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author | Caruso, Martina Stanzione, Arnaldo Ricciardi, Carlo Di Dato, Fabiola Pisani, Noemi Delli Paoli, Gregorio De Giorgi, Marco Liuzzi, Raffaele Mollica, Carmine Romeo, Valeria Iorio, Raffaele Cesarelli, Mario Brunetti, Arturo Maurea, Simone |
author_facet | Caruso, Martina Stanzione, Arnaldo Ricciardi, Carlo Di Dato, Fabiola Pisani, Noemi Delli Paoli, Gregorio De Giorgi, Marco Liuzzi, Raffaele Mollica, Carmine Romeo, Valeria Iorio, Raffaele Cesarelli, Mario Brunetti, Arturo Maurea, Simone |
author_sort | Caruso, Martina |
collection | PubMed |
description | Kasai portoenterostomy (KP) plays a crucial role in the treatment of biliary atresia (BA). The aim is to correlate MRI quantitative findings of native liver survivor BA patients after KP with a medical outcome. Thirty patients were classified as having ideal medical outcomes (Group 1; n = 11) if laboratory parameter values were in the normal range and there was no evidence of chronic liver disease complications; otherwise, they were classified as having nonideal medical outcomes (Group 2; n = 19). Liver and spleen volumes, portal vein diameter, liver mean, and maximum and minimum ADC values were measured; similarly, ADC and T2-weighted textural parameters were obtained using ROI analysis. The liver volume was significantly (p = 0.007) lower in Group 2 than in Group 1 (954.88 ± 218.31 cm(3) vs. 1140.94 ± 134.62 cm(3)); conversely, the spleen volume was significantly (p < 0.001) higher (555.49 ± 263.92 cm(3) vs. 231.83 ± 70.97 cm(3)). No differences were found in the portal vein diameter, liver ADC values, or ADC and T2-weighted textural parameters. In conclusion, significant quantitative morpho-volumetric liver and spleen abnormalities occurred in BA patients with nonideal medical outcomes after KP, but no significant microstructural liver abnormalities detectable by ADC values and ADC and T2-weighted textural parameters were found between the groups. |
format | Online Article Text |
id | pubmed-10045135 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100451352023-03-29 MRI Liver Imaging Integrated with Texture Analysis in Native Liver Survivor Patients with Biliary Atresia after Kasai Portoenterostomy: Correlation with Medical Outcome after Surgical Treatment Caruso, Martina Stanzione, Arnaldo Ricciardi, Carlo Di Dato, Fabiola Pisani, Noemi Delli Paoli, Gregorio De Giorgi, Marco Liuzzi, Raffaele Mollica, Carmine Romeo, Valeria Iorio, Raffaele Cesarelli, Mario Brunetti, Arturo Maurea, Simone Bioengineering (Basel) Article Kasai portoenterostomy (KP) plays a crucial role in the treatment of biliary atresia (BA). The aim is to correlate MRI quantitative findings of native liver survivor BA patients after KP with a medical outcome. Thirty patients were classified as having ideal medical outcomes (Group 1; n = 11) if laboratory parameter values were in the normal range and there was no evidence of chronic liver disease complications; otherwise, they were classified as having nonideal medical outcomes (Group 2; n = 19). Liver and spleen volumes, portal vein diameter, liver mean, and maximum and minimum ADC values were measured; similarly, ADC and T2-weighted textural parameters were obtained using ROI analysis. The liver volume was significantly (p = 0.007) lower in Group 2 than in Group 1 (954.88 ± 218.31 cm(3) vs. 1140.94 ± 134.62 cm(3)); conversely, the spleen volume was significantly (p < 0.001) higher (555.49 ± 263.92 cm(3) vs. 231.83 ± 70.97 cm(3)). No differences were found in the portal vein diameter, liver ADC values, or ADC and T2-weighted textural parameters. In conclusion, significant quantitative morpho-volumetric liver and spleen abnormalities occurred in BA patients with nonideal medical outcomes after KP, but no significant microstructural liver abnormalities detectable by ADC values and ADC and T2-weighted textural parameters were found between the groups. MDPI 2023-02-28 /pmc/articles/PMC10045135/ /pubmed/36978697 http://dx.doi.org/10.3390/bioengineering10030306 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Caruso, Martina Stanzione, Arnaldo Ricciardi, Carlo Di Dato, Fabiola Pisani, Noemi Delli Paoli, Gregorio De Giorgi, Marco Liuzzi, Raffaele Mollica, Carmine Romeo, Valeria Iorio, Raffaele Cesarelli, Mario Brunetti, Arturo Maurea, Simone MRI Liver Imaging Integrated with Texture Analysis in Native Liver Survivor Patients with Biliary Atresia after Kasai Portoenterostomy: Correlation with Medical Outcome after Surgical Treatment |
title | MRI Liver Imaging Integrated with Texture Analysis in Native Liver Survivor Patients with Biliary Atresia after Kasai Portoenterostomy: Correlation with Medical Outcome after Surgical Treatment |
title_full | MRI Liver Imaging Integrated with Texture Analysis in Native Liver Survivor Patients with Biliary Atresia after Kasai Portoenterostomy: Correlation with Medical Outcome after Surgical Treatment |
title_fullStr | MRI Liver Imaging Integrated with Texture Analysis in Native Liver Survivor Patients with Biliary Atresia after Kasai Portoenterostomy: Correlation with Medical Outcome after Surgical Treatment |
title_full_unstemmed | MRI Liver Imaging Integrated with Texture Analysis in Native Liver Survivor Patients with Biliary Atresia after Kasai Portoenterostomy: Correlation with Medical Outcome after Surgical Treatment |
title_short | MRI Liver Imaging Integrated with Texture Analysis in Native Liver Survivor Patients with Biliary Atresia after Kasai Portoenterostomy: Correlation with Medical Outcome after Surgical Treatment |
title_sort | mri liver imaging integrated with texture analysis in native liver survivor patients with biliary atresia after kasai portoenterostomy: correlation with medical outcome after surgical treatment |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045135/ https://www.ncbi.nlm.nih.gov/pubmed/36978697 http://dx.doi.org/10.3390/bioengineering10030306 |
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