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Muscle and Muscle-like Autoantigen Expression in Myasthenia Gravis Thymus: Possible Molecular Hint for Autosensitization

The thymus is widely recognized as an immunological niche where autoimmunity against the acetylcholine receptor (AChR) develops in myasthenia gravis (MG) patients, who mostly present thymic hyperplasia and thymoma. Thymoma-associated MG is frequently characterized by autoantibodies to the muscular r...

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Detalles Bibliográficos
Autores principales: Iacomino, Nicola, Scandiffio, Letizia, Conforti, Fabio, Salvi, Erika, Tarasco, Maria Cristina, Bortone, Federica, Marcuzzo, Stefania, Simoncini, Ornella, Andreetta, Francesca, Pistillo, Daniela, Voulaz, Emanuele, Alloisio, Marco, Antozzi, Carlo, Mantegazza, Renato, De Pas, Tommaso Martino, Cavalcante, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045167/
https://www.ncbi.nlm.nih.gov/pubmed/36979710
http://dx.doi.org/10.3390/biomedicines11030732