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Thiram, an inhibitor of 11ß-hydroxysteroid dehydrogenase type 2, enhances the inhibitory effects of hydrocortisone in the treatment of osteosarcoma through Wnt/β-catenin pathway

BACKGROUND: The anti-osteosarcoma effects of hydrocortisone and thiram, an inhibitor of type 2 11ß-hydroxysteroid dehydrogenase (11HSD2), have not been reported. The purpose of this study was to investigate the effects of hydrocortisone alone or the combination of hydrocortisone with thiram on osteo...

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Detalles Bibliográficos
Autores principales: Zhang, You, Li, Nanjing, Li, He, Chen, Maojia, Jiang, Wei, Guo, Wenhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045229/
https://www.ncbi.nlm.nih.gov/pubmed/36978114
http://dx.doi.org/10.1186/s40360-023-00655-0